Otitis media: recent advances in otitis media vaccine development and model systems

A Zahid, JC Wilson, ID Grice, IR Peak - Frontiers in Microbiology, 2024 - frontiersin.org
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …

Reviewing the Pathogenic Potential of the Otitis-Associated Bacteria Alloiococcus otitidis and Turicella otitidis

R Lappan, SE Jamieson, CS Peacock - Frontiers in cellular and …, 2020 - frontiersin.org
Alloiococcus otitidis and Turicella otitidis are common bacteria of the human ear. They have
frequently been isolated from the middle ear of children with otitis media (OM), though their …

Convolutional neural network approach for automatic tympanic membrane detection and classification

E Başaran, Z Cömert, Y Çelik - Biomedical Signal Processing and Control, 2020 - Elsevier
Otitis media (OM) is a term used to describe the inflammation of the middle ear. The clinical
inspection of the tympanic membrane is conducted visually by experts. Visual inspection …

Fusing fine-tuned deep features for recognizing different tympanic membranes

C Zafer - Biocybernetics and Biomedical Engineering, 2020 - Elsevier
Otitis media (OM) refers to a group of inflammatory diseases regarding the middle ear.
Although there are a wide variety of disease types regarding OM, the most commonly seen …

A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation

KM Khomtchouk, A Kouhi, A Xia, LA Bekale… - Science …, 2020 - science.org
Chronic suppurative otitis media (CSOM) is a neglected pediatric disease affecting 330
million worldwide for which no new drugs have been introduced for over a decade. We …

Establishment of novel immortalized middle ear cell lines as models for otitis media

S Blaine‐Sauer, TL Samuels… - Laryngoscope …, 2023 - Wiley Online Library
Objective Otitis media (OM) is among the most frequently diagnosed pediatric diseases in
the US. Despite the significant public health burden of OM and the contribution research in …

Localized drug delivery to the middle ear: Recent advances and perspectives for the treatment of middle and inner ear diseases

M Magdy, E Elmowafy, M Elassal, RAH Ishak - Journal of Drug Delivery …, 2022 - Elsevier
Traditionally, the majority of ototopical delivery systems are conventional medicated ear
drops. However, their endurance and wide utility is jeopardized due to the presence of an …

Artificial intelligence-driven advancements in otitis media diagnosis: a systematic review

MAH Rony, K Fatema, MAK Raiaan, MM Hassan… - Ieee …, 2024 - ieeexplore.ieee.org
Otitis Media (OM), predominantly affecting children, is a significant global health issue, with
an estimated 360 million pediatric cases yearly worldwide. OM causes mild and moderate …

A model of chronic, transmissible Otitis Media in mice

KK Dewan, DL Taylor-Mulneix, LL Campos… - PLoS …, 2019 - journals.plos.org
Infection and inflammation of the middle ears that characterizes acute and chronic o titis m
edia (OM), is a major reason for doctor visits and antibiotic prescription, particularly among …

PANEL 3: otitis media animal models, cell culture, tissue regeneration & pathophysiology

A Kurabi, K Dewan, JE Kerschner, A Leichtle… - International Journal of …, 2024 - Elsevier
Objective To review and summarize recently published key articles on the topics of animal
models, cell culture studies, tissue biomedical engineering and regeneration, and new …