[HTML][HTML] Lipid-Based Gels for Delivery of 3-O-Ethyl L-Ascorbic acid in Topical Applications

N Loza-Rodríguez, A Millán-Sánchez, M Mallandrich… - Pharmaceutics, 2024 - mdpi.com
This study explores the incorporation of 10% 3-O-ethyl L-ascorbic acid (ETVC), a derivative
of vitamin C, into two lipid gel systems: a hydrogel (HG) consisting exclusively of lipids and …

The role of biophysical properties in defining the functional applications of alkyl esters of L-ascorbic acid

M Mottola, JAV Pérez, ML Fanani - Biochemical and Biophysical Research …, 2025 - Elsevier
Lipophilic derivatives of vitamin C, known as ascorbyl-6-O-alkanoates (ASCn), have been
mainly developed for use in cosmetics, pharmaceuticals, and the food industry as …

Microspheres based on blends of chitosan derivatives with carrageenan as vitamin carriers in cosmeceuticals

K Lewicka, A Smola-Dmochowska, P Dobrzyński… - Polymers, 2024 - mdpi.com
Chitosan (CS) has a natural origin and is a biodegradable and biocompatible polymer with
many skin-beneficial properties successfully used in the cosmetics and pharmaceutical …

Design of novel tricaprylin-incorporated multi-layered liposomal system for skin delivery of ascorbic acid with improved chemical stability

MJ Ho, DW Park, MJ Kang - Pharmaceuticals, 2023 - mdpi.com
L-ascorbic acid (Vit C) possesses a variety of dermatological functions in maintaining skin
health and anti-aging properties. However, its topical application is challenging owing to its …

In vitro assessment of skin permeation properties of enzymatically derived oil‐based fatty acid esters of vitamin C

M Ćorović, M Veljković, A Milivojević… - Archiv der …, 2024 - Wiley Online Library
Current topical formulations containing vitamin C face limitations in therapeutic effectiveness
due to the skin's selective properties that impede drug deposition. Consequently, the …

Preparation and spectroscopic characterization of ternary inclusion complexes of ascorbyl palmitate and urea with γ-cyclodextrin

Y Inoue, A Nanri, FJ Arce, GL See, T Tanikawa… - ChemEngineering, 2023 - mdpi.com
A three-component inclusion complex of ascorbyl palmitate (ASCP), urea (UR), and γ-
cyclodextrin (γCD) with a molar ratio of 1/12 has been prepared for the first time using the …

[PDF][PDF] Permeation Enhancers for Transdermal Drug Delivery: Strategies and Advancements Focusing Macromolecules

P Panda, A Sahu - International Journal of Advanced …, 2023 - ijapsr.latticescipub.com
The various transdermal drug delivery method, allows medications to cross the biological
barriers and enter the bloodstream to elicit desired pharmacological response. The relevant …

Physical Characterization and Sunscreen Activity of Nutmeg Oil Nanoemulsion With Isopropyl Myristate Variations

S Setianingsih, RA Saputro, VR Fauziah… - … Farmasi Sains dan …, 2023 - journal.unimma.ac.id
The nutmeg seed oil contains myristicin which can absorb UV rays. Nanoemulsion with
isopropyl myristate can be used to increase the activity of sunscreen. This study aimed to …

Design of High-Payload Ascorbyl Palmitate Nanosuspensions for Enhanced Skin Delivery

JS Park, JH Choi, MY Joung, IG Yang, YS Choi… - Pharmaceutics, 2024 - mdpi.com
A high-payload ascorbyl palmitate (AP) nanosuspension (NS) was designed to improve skin
delivery following topical application. The AP-loaded NS systems were prepared using the …

Towards development of new antimalarial compounds through in silico and in vitro assays

DBC Junior, PS Lacerda, F de Pilla Varotti… - … Biology and Chemistry, 2024 - Elsevier
Malaria is one of most widespread infectious disease in world. The antimalarial therapy
presents a series of limitations, such as toxicity and the emergence of resistance, which …