Gradient scaffolds for osteochondral tissue engineering and regeneration

B Zhang, J Huang, RJ Narayan - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The tissue engineering approach for repairing osteochondral (OC) defects involves the
fabrication of a biological tissue scaffold that mimics the physiological properties of natural …

Current advances in 3D bioprinting technology and its applications for tissue engineering

JJ Yu, SA Park, WD Kim, T Ha, YZ Xin, JH Lee, D Lee - Polymers, 2020 - mdpi.com
Three-dimensional (3D) bioprinting technology has emerged as a powerful biofabrication
platform for tissue engineering because of its ability to engineer living cells and biomaterial …

Design and bioprinting for tissue interfaces

M Altunbek, F Afghah, OS Caliskan, JJ Yoo… - Biofabrication, 2023 - iopscience.iop.org
Tissue interfaces include complex gradient structures formed by transitioning of biochemical
and mechanical properties in micro-scale. This characteristic allows the communication and …

3D printed multiphasic scaffolds for osteochondral repair: challenges and opportunities

SE Doyle, F Snow, S Duchi, CD O'connell… - International Journal of …, 2021 - mdpi.com
Osteochondral (OC) defects are debilitating joint injuries characterized by the loss of full
thickness articular cartilage along with the underlying calcified cartilage through to the …

Is 3D printing promising for osteochondral tissue regeneration?

D Ege, V Hasirci - ACS Applied Bio Materials, 2023 - ACS Publications
Osteochondral tissue regeneration is quite difficult to achieve due to the complexity of its
organization. In the design of these complex multilayer structures, a fabrication method, 3D …

Progress of platelet derivatives for cartilage tissue engineering

S Wu, W Guo, R Li, X Zhang, W Qu - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Articular cartilage has limited self-regeneration ability for lacking of blood vessels, nerves,
and lymph that makes it a great challenge to repair defects of the tissue and restore motor …

Multilayer functional bionic fabricated polycaprolactone based fibrous membranes for osteochondral integrated repair

Y Hu, X Yin, H Ding, M Kang, S Liang, Y Wei… - Colloids and Surfaces B …, 2023 - Elsevier
Osteochondral defect repair is one of the challenging problems in orthopedics. In this study,
a multilayer polycaprolactone (PCL) based fibrous membrane for osteochondral defect …

Installation of click-type functional groups enable the creation of an additive manufactured construct for the osteochondral interface

IAO Beeren, PJ Dijkstra, AFH Lourenço, R Sinha… - …, 2022 - iopscience.iop.org
Melt extrusion-based additive manufacturing (AM) is often used to fabricate scaffolds for
osteochondral (OC) regeneration. However, there are two shortcomings associated with this …

3D printing of biphasic osteochondral scaffold with sintered hydroxyapatite and polycaprolactone

H Suo, Y Chen, J Liu, L Wang, M Xu - Journal of Materials Science, 2021 - Springer
Biphasic scaffolds with biomimetic structure are essential to osteochondral tissue
engineering. However, insufficient mechanical properties limit their applications. Here, a …

3D printed cell-free bilayer porous scaffold based on alginate with biomimetic microenvironment for osteochondral defect repair

H Wang, J Zhang, H Bai, C Wang, Z Li, Z Wang… - Biomaterials …, 2025 - Elsevier
Despite significant progress in repairing osteochondral injuries using 3D printing
technology, most cartilage layer scaffolds are made of degradable materials, making it …