Extracellular matrix-derived biomaterials in engineering cell function

H Xing, H Lee, L Luo, TR Kyriakides - Biotechnology advances, 2020 - Elsevier
Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

Tendon and ligament healing and current approaches to tendon and ligament regeneration

NL Leong, JL Kator, TL Clemens… - Journal of …, 2020 - Wiley Online Library
Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …

Tendon injuries: Basic science and new repair proposals

F Wu, M Nerlich, D Docheva - EFORT open reviews, 2017 - eor.bioscientifica.com
Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons
become more prone to degeneration followed by injuries. Tendon repair often requires …

Biomaterials in tendon and skeletal muscle tissue engineering: current trends and challenges

M Beldjilali-Labro, A Garcia Garcia, F Farhat, F Bedoui… - Materials, 2018 - mdpi.com
Tissue engineering is a promising approach to repair tendon and muscle when natural
healing fails. Biohybrid constructs obtained after cells' seeding and culture in dedicated …

Production of cultured meat by culturing porcine smooth muscle cells in vitro with food grade peanut wire-drawing protein scaffold

YY Zheng, Y Chen, HZ Zhu, CB Li, WJ Song… - Food Research …, 2022 - Elsevier
Cultivating meat is a promising solution to the negative problems brought by traditional
animal husbandry. To make cultured meat have the sensory and nutritional characteristics of …

In vitro and in vivo effects of IGF-1 delivery strategies on tendon healing: a review

I Miescher, J Rieber, M Calcagni… - International Journal of …, 2023 - mdpi.com
Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation,
leading to inferior mechanical properties and even re-rupture upon resumption of daily work …

[HTML][HTML] Upregulation of FABP4 induced inflammation in the pathogenesis of chronic tendinopathy

Z Ma, AYW Lee, CH Kot, PSH Yung, S Chen… - Journal of Orthopaedic …, 2024 - Elsevier
Objectives Excessive inflammation contributes to the pathogenesis of tendinopathy. Fatty
acid binding protein 4 (FABP4) is a pro-inflammatory adipokine mediating various metabolic …

The functions and mechanisms of tendon stem/progenitor cells in tendon healing

J Lu, H Chen, K Lyu, L Jiang, Y Chen… - Stem Cells …, 2023 - Wiley Online Library
Tendon injury is one of the prevalent disorders of the musculoskeletal system in orthopedics
and is characterized by pain and limitation of joint function. Due to the difficulty of …

Tendon stem progenitor cells: Understanding the biology to inform therapeutic strategies for tendon repair

B Walia, AH Huang - Journal of Orthopaedic Research®, 2019 - Wiley Online Library
Tendon and ligament injuries are a leading cause of healthcare visits with significant impact
in terms of economic cost and reduced quality of life. To date, reparative strategies remain …

Practical considerations for translating mesenchymal stromal cell-derived extracellular vesicles from bench to bed

PPY Lui, YT Leung - Pharmaceutics, 2022 - mdpi.com
Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) have shown
potential for the treatment of tendon and ligament injuries. This approach can eliminate the …