The discovery of antibiotics has saved millions of lives, but the emergence of antibiotic‐
resistant bacteria has become another problem in modern medicine. To avoid or reduce the …

The search for anticancer metal-based drugs alternative to platinum derivatives could not
exclude zinc derivatives due to the importance of this metal for the correct functioning of the …

Pathogens resistant to most conventional anti-infectives are a harbinger of the need to
discover and develop novel anti-infective agents and strategies. Endogenous host defense …

Purpose Cationic host defence peptides constitute a promising class of therapeutic drug
leads with a wide range of therapeutic applications, including anticancer therapy …

Antibiotic-resistant bacterial infections have become global issues for public health, which
increases the utter need to develop alternatives to antibiotics. Here, the HSER (Homo …

β-Lactams have been a clinical focus since their emergence and indeed act as a powerful
tool to combat severe bacterial infections, but their effectiveness is threatened by drug …

The spread of antibiotic resistance among Gram-negative bacteria is a serious clinical
threat, and infections with these organisms are a leading cause of mortality worldwide …

Human serum albumin (HSA) is the dominating protein in human plasma. Many bacterial
species, especially streptococci, express surface proteins that bind HSA with high specificity …

There are many antibiotic-resistant microbial pathogens that have emerged in recent years
causing normal infections to become harder and sometimes impossible to treat. The major …

Abstract The MCPep server (http://bental. tau. ac. il/MCPep/) is designed for non-experts
wishing to perform Monte Carlo (MC) simulations of helical peptides in association with lipid …