Non-canonical DNA structures in the human ribosomal DNA

E Smirnov, P Molínová, N Chmúrčiaková… - Histochemistry and Cell …, 2023 - Springer
Non-canonical structures (NCS) refer to the various forms of DNA that differ from the B-
conformation described by Watson and Crick. It has been found that these structures are …

DNA supercoiling: an ancestral regulator of gene expression in pathogenic bacteria?

S Martis, R Forquet, S Reverchon, W Nasser… - Computational and …, 2019 - Elsevier
DNA supercoiling acts as a global and ancestral regulator of bacterial gene expression. In
this review, we advocate that it plays a pivotal role in host-pathogen interactions by …

Mammalian stem cells reprogramming in response to terahertz radiation

J Bock, Y Fukuyo, S Kang, ML Phipps, LB Alexandrov… - PloS one, 2010 - journals.plos.org
We report that extended exposure to broad-spectrum terahertz radiation results in specific
changes in cellular functions that are closely related to DNA-directed gene transcription. Our …

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

J Duan, J Shi, A Fiorentino, C Leites, X Chen… - The American Journal of …, 2014 - cell.com
Schizophrenia (SZ) genome-wide association studies (GWASs) have identified common risk
variants in> 100 susceptibility loci; however, the contribution of rare variants at these loci …

Specificity and heterogeneity of terahertz radiation effect on gene expression in mouse mesenchymal stem cells

BS Alexandrov, ML Phipps, LB Alexandrov… - Scientific reports, 2013 - nature.com
We report that terahertz (THz) irradiation of mouse mesenchymal stem cells (mMSCs) with a
single-frequency (SF) 2.52 THz laser or pulsed broadband (centered at 10 THz) source …

Non-thermal effects of terahertz radiation on gene expression in mouse stem cells

BS Alexandrov, KØ Rasmussen, AR Bishop… - Biomedical Optics …, 2011 - opg.optica.org
In recent years, terahertz radiation sources are increasingly being exploited in military and
civil applications. However, only a few studies have so far been conducted to examine the …

Ideas and methods of nonlinear mathematics and theoretical physics in DNA science: the McLaughlin-Scott equation and its application to study the DNA open state …

LV Yakushevich, LA Krasnobaeva - Biophysical Reviews, 2021 - Springer
The review is devoted to a new and rapidly developing area related to the application of
ideas and methods of nonlinear mathematics and theoretical physics to study the internal …

Distributions of bubble lifetimes and bubble lengths in DNA

M Hillebrand, G Kalosakas, C Skokos, AR Bishop - Physical Review E, 2020 - APS
We investigate the distribution of bubble lifetimes and bubble lengths in DNA at
physiological temperature, by performing extensive molecular dynamics simulations with the …

0.1 THz exposure affects primary hippocampus neuron gene expression via alternating transcription factor binding

S Shang, XJ Wu, Q Zhang, J Zhao, E Hu… - Biomedical Optics …, 2021 - opg.optica.org
In recent years, many studies have been conducted to investigate the influence of terahertz
(THz) radiation on the gene expression in various cell types, but the underling molecular …

Examining DNA breathing with pyDNA-EPBD

A Kabir, M Bhattarai, KØ Rasmussen, A Shehu… - …, 2023 - academic.oup.com
Motivation The two strands of the DNA double helix locally and spontaneously separate and
recombine in living cells due to the inherent thermal DNA motion. This dynamics results in …