At first glance the nucleus is a highly conserved organelle. Overall nuclear morphology, the
octagonal nuclear pore complex, the presence of peripheral heterochromatin and the …

Trypanosomes are eukaryotic, unicellular parasites, such as Trypanosoma brucei, which
causes sleeping sickness, and Trypanosoma cruzi, which causes Chagas disease …

Trypanosoma cruzi is the causative agent of Chagas disease, a neglected tropical disease,
and one of the most important parasitic diseases worldwide. The first genome of T. cruzi was …

Trypanosoma cruzi, the agent of Chagas disease, must adapt to a diversity of environmental
conditions that it faces during its life cycle. The adaptation to these changes is mediated by …

Through regulation of DNA packaging, histone proteins are fundamental to a wide array of
biological processes. A variety of post-translational modifications (PTMs), including …

Trypanosoma cruzi is a unicellular parasite that causes Chagas disease, which is endemic
in the American continent but also worldwide, distributed by migratory movements. A striking …

RNA–DNA hybrids are epigenetic features of genomes that provide a diverse and growing
range of activities. Understanding of these functions has been informed by characterising …

Chagas is an endemic disease in tropical regions of Latin America, caused by the parasite
Trypanosoma cruzi. High intraspecies variability and genome complexity have been …

Trypanosoma cruzi is the etiologic agent of the most prevalent human parasitic disease in
Latin America, Chagas disease. Its genome is rich in multigenic families that code for …

Histone H2B is a member of the core histones, which together with other histones form the
nucleosome, the basic structural unit of chromosomes. As scientists delve deeper into …