Liver glycogen is synthesized after a meal in response to an increase in blood glucose
concentration in the portal vein and endocrine and neuroendocrine signals, and is degraded …

Abstract A recent International Diabetes Federation report suggests that more than 463
million people between 20 and 79 years have diabetes. Of the 20 million women affected by …

BMP2 and TGFβ1 are functional antagonists of pathological remodeling in the arteries,
heart, and lung; however, the mechanisms in VSMCs, and their disturbance in pulmonary …

Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …

Internationally adopted adolescents who are adopted as young children from conditions of
poverty and deprivation have poorer physical and mental health outcomes than do …

Liver is a metabolically complex organ that influences nutrient partitioning and potentially
modulates the efficiency of converting energy acquired from macronutrients ingestion into a …

Background: Chronic exposure to inorganic arsenic (iAs) has been associated with type 2
diabetes (T2D). However, potential sex divergence and the underlying mechanisms remain …

Ethanol consumption can lead to hepatic steatosis that contributes to late-stage liver
diseases such as cirrhosis and hepatocellular carcinoma. In this study, we investigated the …

The common complications in obesity and type 2 diabetes include hepatic steatosis and
disruption of glucose-glycogen homeostasis, leading to hyperglycemia. Fatty acid …

MYC activation at modest levels has been frequently found in hepatocellular carcinoma.
However, its significance in hepatocarcinogenesis has remained obscure. Here we …