[HTML][HTML] Why is it important to understand the nature and chemistry of tannins to exploit their potential as nutraceuticals?

S Molino, MP Francino, JÁR Henares - Food research international, 2023 - Elsevier
Tannins comprise a large group of polyphenols that can differ widely in chemical
composition and molecular weight. The use of tannins dates back to antiquity, but it is only in …

[HTML][HTML] Uncovering sex-specific mechanisms of action of testosterone and redox balance

D Cruz-Topete, P Dominic, KY Stokes - Redox Biology, 2020 - Elsevier
The molecular and pharmacological manipulation of the endogenous redox system is a
promising therapy to limit myocardial damage after a heart attack; however, antioxidant …

Ehrlich ascites carcinoma as model for studying the cardiac protective effects of curcumin nanoparticles against cardiac damage in female mice

B Alotaibi, E Tousson, TA El‐Masry… - Environmental …, 2021 - Wiley Online Library
While clinical innovation has improved, cancer or malignant growth stays a genuine medical
issue and has been perceived as a significant factor in mortality and morbidity. Current work …

Hepatic ameliorative role of vitamin B17 against Ehrlich ascites carcinoma–induced liver toxicity

E Tousson, E Hafez, MM Abo Gazia, SB Salem… - … Science and Pollution …, 2020 - Springer
Abstract Vitamin B17 (VB17), also known as amygdalin and laetrile, is a type of
carbohydrate occurring naturally in many plants, such as apricot kernels which have …

Pharmacology and toxicology of tannins

A Maugeri, GE Lombardo, S Cirmi, I Süntar… - Archives of …, 2022 - Springer
Tannins are an interesting class of polyphenols, characterized, in almost all cases, by a
different degree of polymerization, which, inevitably, markedly influences their …

[HTML][HTML] Flavonoids in myocardial ischemia-reperfusion injury: Therapeutic effects and mechanisms

J Jia, E Zang, L Lv, Q Li, C Zhang, Y Xia, L Zhang… - Chinese Herbal …, 2021 - Elsevier
Ischemic heart diseases are one of the major causes of death worldwide. Effective
restoration of blood flow can significantly improve patients' quality of life and reduce …

Antioxidant/pro-oxidant actions of polyphenols from grapevine and wine by-products-base for complementary therapy in ischemic heart diseases

VS Chedea, LL Tomoiagǎ, ŞO Macovei… - Frontiers in …, 2021 - frontiersin.org
Grape pomace and grape seeds, by-products of the wine industry, and grapevine cane
resulting from grapevine pruning are cheap matrices containing important amounts of …

Potential implications of natural compounds on aging and metabolic regulation

Z Li, L Chen, L Qu, W Yu, T Liu, F Ning, J Li… - Ageing Research …, 2024 - Elsevier
Aging is generally accompanied by a progressive loss of metabolic homeostasis. Targeting
metabolic processes is an attractive strategy for healthy-aging. Numerous natural …

[HTML][HTML] Grape seeds proanthocyanidin extract ameliorates Ehrlich solid tumor induced renal tissue and DNA damage in mice

MA Abd Eldaim, E Tousson, IET El Sayed… - Biomedicine & …, 2019 - Elsevier
The current study was carried out to evaluate the protective effect of grape seed
proanthocyanidins extract (GSPE) against Ehrlich solid tumor (EST) induced renal injury …

Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin‐Induced Organ Dysfunction in Rats: Comprehensive in vivo …

M Chandra Shill, HAS El‐Nashar… - Chemistry & …, 2024 - Wiley Online Library
This study focused to assess the efficacy of Gynura procumbens (GP) leaf extract against
cisplatin (CP)‐induced hepatorenal complications in Wister albino rats. Additionally, it aims …