Variable regions of antibodies and T-cell Receptors may not be sufficient in molecular simulations investigating binding

B Knapp, J Dunbar, M Alcala… - Journal of chemical theory …, 2017 - ACS Publications
Antibodies and T-cell receptors are important proteins of the immune system that share
similar structures. Both contain variable and constant regions. Insight into the dynamics of …

Exploring the different states of wild-type T-cell receptor and mutant conformational changes towards understanding the antigen recognition

SK Tripathi, DM Salunke - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Recognition of proteolytic peptide fragments presented by major histocompatibility complex
(MHC) on target cells by T-cell receptor (TCR) is among the most important interactions in …