Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure
DL Eizirik, L Pasquali, M Cnop - Nature Reviews Endocrinology, 2020 - nature.com
Loss of functional β-cell mass is the key mechanism leading to the two main forms of
diabetes mellitus—type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) …
diabetes mellitus—type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) …
[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2022: Stages of type 1 diabetes in children and adolescents.
ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …
adolescents Page 1 ISPAD GUIDELINES ISPAD clinical practice consensus guidelines 2022 …
[PDF][PDF] ISPAD Clinical Practice Consensus Guidelines 2022: Definition, epidemiology, and classification of diabetes in children and adolescents.
I Libman, A Haynes, S Lyons, P Pradeep… - Pediatric …, 2022 - digibete.org
This chapter serves as an update and replaces the 2018 ISPAD consensus guideline on
definition, epidemiology, and classification of diabetes in children and adolescents. 1 It …
definition, epidemiology, and classification of diabetes in children and adolescents. 1 It …
Type 1 diabetes
Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …
[HTML][HTML] Diabetes mellitus: The epidemic of the century
AT Kharroubi, HM Darwish - World journal of diabetes, 2015 - ncbi.nlm.nih.gov
The epidemic nature of diabetes mellitus in different regions is reviewed. The Middle East
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …
and North Africa region has the highest prevalence of diabetes in adults (10.9%) whereas …
[HTML][HTML] Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
Background Type 1 diabetes is typically considered a disease of children and young adults.
Genetic susceptibility to young-onset type 1 diabetes is well defined and does not …
Genetic susceptibility to young-onset type 1 diabetes is well defined and does not …
Genetic risk scores for diabetes diagnosis and precision medicine
During the last decade, there have been substantial advances in the identification and
characterization of DNA sequence variants associated with individual predisposition to type …
characterization of DNA sequence variants associated with individual predisposition to type …
Development and standardization of an improved type 1 diabetes genetic risk score for use in newborn screening and incident diagnosis
OBJECTIVE Previously generated genetic risk scores (GRSs) for type 1 diabetes (T1D) have
not captured all known information at non-HLA loci or, particularly, at HLA risk loci. We …
not captured all known information at non-HLA loci or, particularly, at HLA risk loci. We …
Genetics of type 1 diabetes
MJ Redondo, AK Steck, A Pugliese - Pediatric diabetes, 2018 - Wiley Online Library
Type 1 diabetes (T1D) results from immune‐mediated loss of pancreatic beta cells leading
to insulin deficiency. It is the most common form of diabetes in children, and its incidence is …
to insulin deficiency. It is the most common form of diabetes in children, and its incidence is …
A type 1 diabetes genetic risk score can aid discrimination between type 1 and type 2 diabetes in young adults
OBJECTIVE With rising obesity, it is becoming increasingly difficult to distinguish between
type 1 diabetes (T1D) and type 2 diabetes (T2D) in young adults. There has been …
type 1 diabetes (T1D) and type 2 diabetes (T2D) in young adults. There has been …