Protein-based bioactive coatings: from nanoarchitectonics to applications

C Fu, Z Wang, X Zhou, B Hu, C Li, P Yang - Chemical Society Reviews, 2024 - pubs.rsc.org
Protein-based bioactive coatings have emerged as a versatile and promising strategy for
enhancing the performance and biocompatibility of diverse biomedical materials and …

Functional Ligand-Enabled Particle Assembly for Bio–Nano Interactions

Y Ju, CJ Kim, F Caruso - Accounts of Chemical Research, 2023 - ACS Publications
Conspectus Functional ligands consist of a wide range of small or large molecules that
exhibit a spectrum of physical, chemical, and biological properties. A suite of small …

Approaching Two Decades: Biomolecular Coronas and Bio–Nano Interactions

S Li, C Cortez-Jugo, Y Ju, F Caruso - ACS nano, 2024 - ACS Publications
It has been nearly two decades since the term “protein corona” was coined. This term has
since evolved to “biomolecular corona” or “biocorona” to capture the diverse biomolecules …

Poly (ethylene glycol) Cross-Linked Antibody Nanoparticles for Tunable Biointeractions

Y Hu, C Cortez-Jugo, Y Ju, T Zheng, J Zhou… - Chemistry of …, 2023 - ACS Publications
Liver accumulation of nanoparticles is a major challenge in nanoparticle-mediated delivery
as it can reduce the delivery of the nanoparticles to their intended site and lead to liver …

Engineering poly (ethylene glycol) particles for targeted drug delivery

S Li, Y Ma, J Cui, F Caruso, Y Ju - Chemical Communications, 2024 - pubs.rsc.org
Poly (ethylene glycol)(PEG) is considered to be the “gold standard” among the stealth
polymers employed for drug delivery. Using PEG to modify or engineer particles has thus …

Interactions between nanoparticle corona proteins and the immune system

TTM Tran, SR Roffler - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•Natural IgG antibodies can bind to NPs and activate complement.•SARS-CoV-2
mRNA vaccines increase the titers of anti-PEG antibodies in recipients.•Anti-PEG antibodies …

Active regulation of protein coronas for enhancing the in vivo biodistribution and metabolism of nanoparticles

D Jin, M Liu, Y Zhang, W Yu, J Yu, Y Luo… - Inorganic Chemistry …, 2024 - pubs.rsc.org
Nanomaterials inevitably acquire protein coronas upon in vivo administration. The fate of
nanoparticles is dynamically influenced by the composition of these protein coronas, which …

Phenolic Ligand–Metal Charge Transfer Induced Copper Nanozyme with Reactive Oxygen Species-Scavenging Ability for Chronic Wound Healing

Y Chen, X Yang, K Li, J Feng, X Liu, Y Li, K Yang, J Li… - ACS …, 2024 - ACS Publications
Chronic wounds frequently arise as a complication in diabetic patients, and their
management remains a significant clinical hurdle due to their nonhealing nature featured by …

Nanoparticle Association with Brain Cells Is Augmented by Protein Coronas Formed in Cerebrospinal Fluid

C Rennie, N Morshed, M Faria… - Molecular …, 2025 - ACS Publications
Neuronanomedicine harnesses nanoparticle technology for the treatment of neurological
disorders. An unavoidable consequence of nanoparticle delivery to biological systems is the …

Phospholipid Type Regulates Protein Corona Composition and In Vivo Performance of Lipid Nanodiscs

F Pan, M Liu, G Li, B Chen, Y Chu, Y Yang… - Molecular …, 2024 - ACS Publications
Over the years, there has been significant interest in PEGylated lipid-based nanocarriers
within the drug delivery field. The inevitable interplay between the nanocarriers and plasma …