Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Drug delivery systems (DDS) are defined as methods by which drugs are delivered to
desired tissues, organs, cells and subcellular organs for drug release and absorption …

Mitochondria, which play central roles in immunometabolic diseases, have their own
genome. However, the functions of mitochondria-located noncoding RNAs are largely …

Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

The design and development of tumor microenvironment (TME)-responsive intelligent
nanoplatforms have attracted increasing interest to enhance the therapeutic effects of drugs …

The intrinsic limits of conventional cancer therapies prompted the development and
application of various nanotechnologies for more effective and safer cancer treatment …

The application of nanoparticles (NPs) to drug delivery has led to the development of novel
nanotherapeutics for the treatment of various diseases including cancer. However, clinical …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Since the revolutionary discovery of RNA interference (RNAi), a remarkable progress has
been achieved in understanding and harnessing gene silencing mechanism; especially in …

As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …