Clinical translation of silica nanoparticles

TI Janjua, Y Cao, C Yu, A Popat - Nature Reviews Materials, 2021 - nature.com
Silica nanoparticles have entered clinical trials for a variety of biomedical applications,
including oral drug delivery, diagnostics, plasmonic resonance and photothermal ablation …

[HTML][HTML] Biosafety of mesoporous silica nanoparticles; towards clinical translation

A Lérida-Viso, A Estepa-Fernández… - Advanced Drug Delivery …, 2023 - Elsevier
Mesoporous silica nanoparticles (MSNs) have attracted the attention of chemists, who have
developed numerous systems for the encapsulation of a plethora of molecules, allowing the …

[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers

TI Janjua, Y Cao, F Kleitz, M Linden, C Yu… - Advanced Drug Delivery …, 2023 - Elsevier
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …

Biomedical applications of mesoporous silica nanoparticles as a drug delivery carrier

H Ahmed, SS Gomte, E Prathyusha… - Journal of Drug Delivery …, 2022 - Elsevier
Mesoporous silica nanoparticles (MSNs) attracted biomedical researchers due to their
unique properties like large surface area, pore-volume, and surface-active groups. These …

Mesoporous silica nanoparticles as a potential nanoplatform: therapeutic applications and considerations

K Djayanti, P Maharjan, KH Cho, S Jeong… - International Journal of …, 2023 - mdpi.com
With advances in nanotechnology, nanoparticles have come to be regarded as carriers of
therapeutic agents and have been widely studied to overcome various diseases in the …

Glutathione-Exhausting Nanoprobes for NIR-II fluorescence imaging-guided surgery and boosting Radiation Therapy Efficacy via Ferroptosis in breast Cancer

M Wei, J Bai, X Shen, K Lou, Y Gao, R Lv, P Wang… - ACS …, 2023 - ACS Publications
Breast-conserving surgery (BCS) is the standard of care for early breast cancer patients,
while the high ratio of reoperation is still a challenge due to inaccurate margin assessments …

Oxygen‐Deficient Bioceramics: Combination of Diagnosis, Therapy, and Regeneration

A Bigham, MG Raucci, K Zheng… - Advanced …, 2023 - Wiley Online Library
The journey of ceramics in medicine has been synchronized with an evolution from the first
generation—alumina, zirconia, etc.—to the third—3D scaffolds. There is an up‐and‐coming …

Current status of silica-based nanoparticles as therapeutics and its potential as therapies against viruses

DJH Tng, JGH Low - Antiviral Research, 2023 - Elsevier
In the past decade, interest in nanoparticles for clinical indications has been steadily gaining
traction. Most recently, Lipid Nanoparticles (LNP) have been used successfully to construct …

Nanoarchitectured prototypes of mesoporous silica nanoparticles for innovative biomedical applications

RK Kankala, YH Han, HY Xia, SB Wang… - Journal of …, 2022 - Springer
Despite exceptional morphological and physicochemical attributes, mesoporous silica
nanoparticles (MSNs) are often employed as carriers or vectors. Moreover, these …

[HTML][HTML] Polymeric nanocomposite hydrogel scaffold for jawbone regeneration: The role of rosuvastatin calcium-loaded silica nanoparticles

IM Adel, MF ElMeligy, MS Amer… - International Journal of …, 2023 - Elsevier
Bones are subject to different types of damages ranging from simple fatigue to profound
defects. In serious cases, the endogenous healing mechanism is not capable of healing the …