Protein cargo in extracellular vesicles as the key mediator in the progression of cancer

K Hánělová, M Raudenská, M Masařík… - Cell Communication and …, 2024 - Springer
Exosomes are small vesicles of endosomal origin that are released by almost all cell types,
even those that are pathologically altered. Exosomes widely participate in cell-to-cell …

The role of biomechanical stress in extracellular vesicle formation, composition and activity

W Thompson, ET Papoutsakis - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are cornerstones of intercellular communication with exciting
fundamental, clinical, and more broadly biotechnological applications. However, variability …

Hijacking homeostasis: Regulation of the tumor microenvironment by apoptosis

CD Gregory - Immunological reviews, 2023 - Wiley Online Library
Cancers are genetically driven, rogue tissues which generate dysfunctional, obdurate
organs by hijacking normal, homeostatic programs. Apoptosis is an evolutionarily conserved …

[HTML][HTML] Cellular stress management by caspases

LA Baena-Lopez, L Wang, F Wendler - Current Opinion in Cell Biology, 2024 - Elsevier
Cellular stress plays a pivotal role in the onset of numerous human diseases. Consequently,
the removal of dysfunctional cells, which undergo excessive stress-induced damage via …

RNAs in tumour‐derived extracellular vesicles and their significance in the tumour microenvironment

M Bugajova, M Raudenska, M Masarik… - … Journal of Cancer, 2024 - Wiley Online Library
Small extracellular vesicles (sEVs) secreted by various types of cells serve as crucial
mediators of intercellular communication within the complex tumour microenvironment …

Harnessing genomic analysis to explore the role of telomeres in the pathogenesis and progression of diabetic kidney disease

C Hill, S Duffy, T Coulter, AP Maxwell, AJ McKnight - Genes, 2023 - mdpi.com
The prevalence of diabetes is increasing globally, and this trend is predicted to continue for
future decades. Research is needed to uncover new ways to manage diabetes and its co …

Oxidative stress‐induced changes in the transcriptomic profile of extracellular vesicles

ER Dellar, C Hill, DRF Carter… - Journal of Extracellular …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) have been proposed to play dual roles in cellular homeostasis,
functioning both to remove unwanted intracellular molecules, and to enable communication …

[HTML][HTML] Menthol induces extracellular vesicle regulation of apoptosis via ATG3 and caspase-3 in acute leukemic cells

K Charoensedtasin, M Naksawat, C Norkaew… - Heliyon, 2024 - Elsevier
Leukemia is one of the most deadly cancers in Thailand. Natural compounds have been
developed for cancer treatment. Menthol, a peppermint compound, has shown …

Uncovering the bequeathing potential of Apoptotic Mesenchymal Stem Cells via small Extracellular Vesicles for its enhanced immunomodulatory ability

M Mendiratta, M Mendiratta, Y Sharma, RK Sahoo… - bioRxiv, 2024 - biorxiv.org
Small Extracellular Vesicles (sEVs) derived from Mesenchymal Stem Cells (MSCs) have
emerged as a promising avenue for cell-free therapeutics in regenerative medicine. These …

[PDF][PDF] Communication between midgut enterocytes and other cell types in adult Drosophila

J Zhang - 2024 - savoirs.usherbrooke.ca
The intestine performs various functions, one of which is to establish a physical barrier to
prevent the infiltration of harmful agents or pathogens from ingested food (Jasper, 2020) …