[HTML][HTML] Therapeutic potential of induced iron depletion using iron chelators in Covid-19

PP Naseef, M Elayadeth-Meethal, KTM Salim… - Saudi Journal of …, 2022 - Elsevier
Ferritin, which includes twenty-four light and heavy chains in varying proportions in different
tissues, is primarily responsible for maintaining the body's iron metabolism. Its normal value …

Targeting pro-oxidant iron with deferoxamine as a treatment for ischemic stroke: safety and optimal dose selection in a randomized clinical trial

M Millán, N DeGregorio-Rocasolano… - Antioxidants, 2021 - mdpi.com
A role of iron as a target to prevent stroke-induced neurodegeneration has been recently
revisited due to new evidence showing that ferroptosis inhibitors are protective in …

[HTML][HTML] Association between iron deposition in splenic, hepatic and myocardial tissues assessed by T2* relaxometry technique

A Mohammadzadeh, S Alizadeh, L Shojaie… - Caspian Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Decreasing signal intensity of the spleen assessed by T2* MRI is a frequent
finding in patients with beta-thalassemia due to iron deposition within the reticuloendothelial …

Metals and metal antagonists

JP Gray, JR Kim, SD Ray - Side effects of drugs annual, 2019 - Elsevier
The side effects of drugs annuals forms a series of volumes in which the adverse effects of
drugs and adverse reactions to them are surveyed. The series supplements the contents of …

Use of rapid cardiac magnetic resonance imaging to guide chelation therapy in patients with transfusion-dependent thalassaemia in India: UMIMI study

KM Medina, A Abdel-Gadir, K Ganga… - … Journal-Quality of …, 2022 - academic.oup.com
Aims To explore the impact of incorporating a faster cardiac magnetic resonance (CMR)
imaging protocol in a low–middle-income country (LMIC) and using the result to guide …

New insights into oxidative damage and iron associated impairment in traumatic brain injury

N Toro-Urrego, LF Turner… - Current …, 2019 - ingentaconnect.com
Traumatic Brain Injury is considered one of the most prevalent causes of death around the
world; more than seventy millions of individuals sustain the condition per year. The …

Comparison of Deferasirox and Desferrioxamine in Term of Mean Serum Ferritin Levels in Patients of β-Thalassemia Major with Iron Overload: Effect of Deferasirox …

K Iram, Z Ali, F Aamer, A Shiekh… - Pakistan Journal of …, 2024 - mail.thejas.com.pk
Iron chelation treatments as adjuvant therapy can reduce iron stores to minimize the related
morbidity and mortality in patients with thalassemia major. Objective: To compare …

Improving the Access of Cardiac Magnetic Resonance in Low-Middle Income Countries to Improve Cardiac Care: Rapid CMR

KD Menacho Medina - 2022 - discovery.ucl.ac.uk
Non-communicable diseases–cancer and cardiovascular disease-are the leading causes of
death in high-income countries (HICs). Cardiovascular disease, however, is increasing in …

[PDF][PDF] COMPARATIVE EFFICACY AND SAFETY OF ORAL IRON CHELATORS AND THEIR NOVEL COMBINATION IN CHILDREN WITH THALASSEMIA

MN Rao, S Sana - Int J Acad Med Pharm, 2022 - academicmed.org
Background:" Thalassemia" refers to anemias caused by hereditary defects in haemoglobin
synthesis. These hereditary illnesses are common in the Mediterranean region, the Indian …

Role of Hydroxyurea in Patients of Beta Thalassemia Majo

B Fatima, STH Zaidi, A Saba, M Samina… - Pakistan Armed Forces …, 2022 - pafmj.org
Results: The mean age of study subjects was 9.15±3.99 years, and most study subjects
(56.14%) were boys. The preintervention (before administration of Hydroxyurea) levels of …