Complications arising from diabetes can threaten multiple organs. Advanced glycation end
products (AGEs) play a significant role in inducing these complications. Highly processed …

The NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome has been
linked to the release of pro-inflammatory cytokines and is essential for innate defence …

Type-2 diabetes mellitus is a prime factor for the development of Diabetic Nephropathy (DN)
that affects the vital organ namely the kidneys, and further alters the functions of the nephron …

This study aimed to determine the potential protective effects of chrysin (CHR) on
experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into …

Diabetic nephropathy (DN) is a renal complication of diabetic hyperglycemia. The Signal
transducer and activator of transcription 3 (Stat3) is a center molecule of the chronic …

Nephropathy is the most prevalent microvascular disorder in diabetes mellitus. Oxidative
stress and inflammatory cascade provoked by the persistent hyperglycemic milieu play …

Liver fibrosis is one of the leading causes of hepatic sclerosis and hepatocellular carcinoma
worldwide. However, the complex pathophysiological mechanisms of liver fibrosis are …

Acute liver injury (ALI), often caused by viruses, alcohol, drugs, etc., is one of the most
common clinical liver diseases. Although pyroptosis plays an important role in ALI, there is …

The current study aims to assess the protective effects of dapagliflozin (Dapa; a sodium-
glucose cotransporter-2 inhibitor) and/or liraglutide (Lira; a glucagon-like peptide 1 agonist) …

Losartan has a significant renal protection effect in type 2 diabetic patients. It was loaded
into bilosomes to overcome its low oral bioavailability and improve its renal protective …