The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

Gregoire, Francine M., Cynthia M. Smas, and Hei Sook Sul. Understanding Adipocyte
Differentiation. Physiol. Rev. 78: 783–809, 1998.—The adipocyte plays a critical role in …

Prostanoids are the cyclooxygenase metabolites of arachidonic acid and include
prostaglandin (PG) D2, PGE2, PGF2α, PGI2, and thromboxne A2. They are synthesized and …

Obesity-associated low-grade inflammation of white adipose tissue (WAT) contributes to
development of insulin resistance and other disorders. Accumulation of immune cells …

The importance of a high fat intake in the increasing prevalence of childhood and adult
obesity remains controversial. Moreover, qualitative changes (ie the fatty acid composition of …

The renin-angiotensin system has long been recognized as an important regulator of
systemic blood pressure and renal electrolyte homeostasis, and local renin-angiotensin …

Overfeeding of rodents leads to increased local formation of angiotensin II due to increased
secretion of angiotensinogen from adipocytes. Whereas angiotensin II promotes adipocyte …

Peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear hormone
receptor expressed predominantly in adipose tissue, where it plays a central role in the …

In this study multipotent adipose-derived stem cells isolated from human adipose tissue
(hMADS cells) were shown to differentiate into adipose cells in serum-free, chemically …

High fat intake is associated with fat mass gain through fatty acid activation of peroxisome
proliferator-activated receptors δ and γ, which promote adipogenesis. We show herein that …