Protease inhibitors from plants as therapeutic agents-a review

MS Cid-Gallegos, LJ Corzo-Ríos… - Plant Foods for Human …, 2022 - Springer
Plant-based diets are a great source of protease inhibitors (PIs). Two of the most well-known
families of PIs are Bowman-Birk inhibitors (BBI) and Kunitz-type inhibitors (KTI). The first …

Biotechnological, biomedical, and agronomical applications of plant protease inhibitors with high stability: A systematic review

J Cotabarren, D Lufrano, MG Parisi, WD Obregón - Plant Science, 2020 - Elsevier
Protease inhibitors (PIs) are regulatory proteins found in numerous animal tissues and
fluids, plants, and microorganisms that reduce and inhibit the exacerbated and uncontrolled …

Trypsin inhibitors: promising candidate satietogenic proteins as complementary treatment for obesity and metabolic disorders?

V Cristina Oliveira de Lima, G Piuvezam… - Journal of enzyme …, 2019 - Taylor & Francis
The increase in non-communicable chronic diseases has aroused interest in the research of
adjuvants to the classic forms of treatments. Obesity and metabolic syndrome are the main …

Marine natural products with anti-inflammatory activity

RCF Cheung, TB Ng, JH Wong, Y Chen… - Applied microbiology and …, 2016 - Springer
Chronic inflammation is believed to play crucial roles in the pathogenesis of various
diseases. Several types of drugs are used to treat inflammatory disorders, but they cause …

[HTML][HTML] Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic …

JANC Ribeiro, AC Serquiz, PFS Silva, PBBM Barbosa… - Clinics, 2015 - SciELO Brasil
OBJECTIVES: Seeds are excellent sources of proteinase inhibitors, some of which may
have satietogenic and slimming actions. We evaluated the effect of a trypsin inhibitor from …

[HTML][HTML] Erythrina velutina Willd.: A review of its traditional uses, phytochemistry, pharmacology, and toxicology

TL Adetunji, MA Acho, VO Samuel, CR Ohoro… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Erythrina velutina Willd., commonly known as
“mulungu” in Brazil, is a leguminous tree with various traditional medicinal uses. These uses …

GdTI, the first thermostable trypsin inhibitor from Geoffroea decorticans seeds. A novel natural drug with potential application in biomedicine

J Cotabarren, DJ Broitman, E Quiroga… - International Journal of …, 2020 - Elsevier
A novel thermostable trypsin inhibitor was obtained from Geoffroea decorticans seeds. G.
decorticans trypsin inhibitor (GdTI) is a protein with molecular mass of 6743.7 Da, with a …

Anti-TNF-α Agent Tamarind Kunitz Trypsin Inhibitor Improves Lipid Profile of Wistar Rats Presenting Dyslipidemia and Diet-induced Obesity Regardless of PPAR-γ …

FMC Carvalho, VCO Lima, IS Costa, ABS Luz… - Nutrients, 2019 - mdpi.com
The increasing prevalence of obesity and, consequently, chronic inflammation and its
complications has increased the search for new treatment methods. The effect of the purified …

Bioactivities of pseudocereal fractionated seed proteins and derived peptides relevant for maintaining human well-being

J Capraro, SD Benedetti, GC Heinzl… - International Journal of …, 2021 - mdpi.com
Food proteins and peptides are able to exert a variety of well-known bioactivities, some of
which are related to well-being and disease prevention in humans and animals. Currently …

A trypsin inhibitor from tamarind reduces food intake and improves inflammatory status in rats with metabolic syndrome regardless of weight loss

FMC Carvalho, VCO Lima, IS Costa, AF Medeiros… - Nutrients, 2016 - mdpi.com
Trypsin inhibitors are studied in a variety of models for their anti-obesity and anti-
inflammatory bioactive properties. Our group has previously demonstrated the satietogenic …