Intraperitoneal chromophore injections delay early-onset and rapid retinal cone degeneration in a mouse model of Leber congenital Amaurosis

X Dai, X Jin, Q Ye, H Huang, L Duo, C Lu, J Bao… - Experimental Eye …, 2021 - Elsevier
Highly expressed in the retinal pigment epithelium (RPE), the RPE-specific 65-kDa (RPE65)
enzyme is indispensable to generate 11-cis-retinal (11cRAL), a chromophore for rhodopsin …