Emerging lipid–polymer hybrid nanoparticles for genome editing

M Gameiro, JF Mano, VM Gaspar - Polymer Chemistry, 2024 - pubs.rsc.org
Genome editing technologies have been key to unlocking new bioengineering strategies as
they enable the modification of mammalian cells' genes in a fully user-programmed mode …

Lipo-polymeric nano-complexes for dermal delivery of a model protein

A Tharmatt, DK Sahel, R Jatyan, A Kumari, A Mishra… - RSC …, 2024 - pubs.rsc.org
Delivering macromolecules across the skin poses challenges due to the barrier properties of
stratum corneum. Different strategies have been reported to cross this barrier, such as …

cRGD-modified hybrid lipopolymeric nanoplexes for gene editing in the posterior segment of the eye

DK Sahel, SG Goswami, R Jatyan, A Tharmatt… - International Journal of …, 2024 - Elsevier
Eye-related diseases, specifically retinal dystrophy (RD) conditions, are the leading cause of
blindness worldwide. Gene addition, regulation, or editing could potentially treat such …