Concise review: comparison of culture membranes used for tissue engineered conjunctival epithelial equivalents

JR Eidet, DA Dartt, TP Utheim - Journal of functional biomaterials, 2015 - mdpi.com
The conjunctival epithelium plays an important role in ensuring the optical clarity of the
cornea by providing lubrication to maintain a smooth, refractive surface, by producing …

Clinical outcomes of xeno-free expansion and transplantation of autologous ocular surface epithelial stem cells via contact lens delivery: a prospective case series

S Bobba, S Chow, S Watson, N Di Girolamo - Stem Cell research & …, 2015 - Springer
Introduction Depletion of limbal stem cells leads to a debilitating condition known as limbal
stem cell deficiency, characterised by impaired corneal wound healing and poor vision. The …

New approaches to ocular surface reconstruction beyond the cornea

K Spaniol, C Holtmann, G Geerling, S Schrader - Der Ophthalmologe, 2017 - Springer
Background Reconstruction of the conjunctiva is an essential part of ocular surface
reconstruction. Clinically applied and experimentally tested tissue-and stem-cell-based …

Vitrified collagen-based conjunctival equivalent for ocular surface reconstruction

H Zhou, Q Lu, Q Guo, J Chae, X Fan, JH Elisseeff… - Biomaterials, 2014 - Elsevier
The main functions of the conjunctiva, an essential part of the ocular surface, are to maintain
the equilibrium of the tear film and to protect the eye. Upon injuries, the prerequisite to …

Development of decellularized conjunctiva as a substrate for the ex vivo expansion of conjunctival epithelium

S Kasbekar, SB Kaye, RL Williams… - Journal of Tissue …, 2018 - Wiley Online Library
This study was performed to develop a method to decellularize human conjunctiva and to
characterize the tissue in terms of its deoxyribose nucleic acid (DNA) content, tensile …

Molecular layer deposition builds biocompatible substrates for epithelial cells

L Momtazi, DA Dartt, O Nilsen… - Journal of Biomedical …, 2018 - Wiley Online Library
The demand for novel biocompatible materials as surface coating in the field of regenerative
medicine is high. We explored molecular layer deposition (MLD) technique for building …

Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells

R Islam, JR Eidet, RA Badian, M Lippestad… - Scientific Reports, 2017 - nature.com
Transplantation of cultured oral mucosal epithelial cells (OMECs) is a promising treatment
strategy for limbal stem cell deficiency. In order to improve the culture method, we …

[图书][B] Development of substrates for the ex vivo expansion of conjunctival epithelium

S Kasbekar - 2016 - search.proquest.com
The conjunctiva is a mucous membrane lining the ocular surface and is crucial to ocular
surface homeostasis. Ocular surface diseases lead to a poor tear film, irreversible …

[PDF][PDF] tissue Harvesting site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells

M Griffith, DA Dartt, TP Utheim - academia.edu
Methods EpiLife medium, EpiLife defined growth supplement (EDGS), and trypsin-EDTA
were purchased from Life Technologies (Grand Island, NY). Oral keratinocyte medium, oral …

MODELS AND THERAPEUTICS FOR ENGINEERING THE OCULAR SURFACE

Q Lu - 2017 - jscholarship.library.jhu.edu
The ocular surface is the outermost part of the eye that protects the refractive surface and
enables sharp vision. The primary components of the ocular surface are corneal and …