The purpose of this paper is to provide an integrative review and offer novel insights
regarding human research with classic psychedelics (classic hallucinogens), which are …

Extensive studies showed that monoaminergic neurotransmission that involves serotonin (5-
HT), norepinephrine (NE) and dopamine (DA) exerts major influence on brain circuits …

Objective: Imaging studies of major depressive disorder have reported structural and
functional abnormalities in a variety of spatially diverse brain regions. Quantitative meta …

'How Emotions Are Made did what all great books do. It took a subject I thought I understood
and turned my understanding upside down'–Malcolm Gladwell, author of The Tipping Point …

Recent resting-state functional connectivity magnetic resonance imaging studies have
shown significant group differences in several regions and networks between patients with …

The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

Increasing evidence points to an association between major depressive disorders (MDDs)
and diverse types of GABAergic deficits. In this review, we summarize clinical and preclinical …

Background Subcallosal cingulate white matter (SCC) deep brain stimulation (DBS) is an
evolving investigational treatment for depression. Mechanisms of action are hypothesized to …

Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …

Treatment-resistant depression is a severely disabling disorder with no proven treatment
options once multiple medications, psychotherapy, and electroconvulsive therapy have …