Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

Hyperpolarized water as universal sensitivity booster in biomolecular NMR

C Hilty, D Kurzbach, L Frydman - Nature protocols, 2022 - nature.com
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …

Hypershifted spin spectroscopy with dynamic nuclear polarization at 1.4 K

Z Pang, K Sheberstov, BA Rodin, J Lumsden… - Science …, 2024 - science.org
Dynamic nuclear polarization (DNP) enhances nuclear magnetic resonance (NMR)
sensitivity by transferring polarization from unpaired electrons to nuclei, but nearby nuclear …

Hyperpolarized NMR Metabolomics at Natural 13C Abundance

A Dey, B Charrier, E Martineau, C Deborde… - Analytical …, 2020 - ACS Publications
Metabolomics plays a pivotal role in systems biology, and NMR is a central tool with high
precision and exceptional resolution of chemical information. Most NMR metabolomic …

Practical dissolution dynamic nuclear polarization

SJ Elliott, Q Stern, M Ceillier, T El Daraï… - Progress in Nuclear …, 2021 - Elsevier
This review article intends to provide insightful advice for dissolution-dynamic nuclear
polarization in the form of a practical handbook. The goal is to aid research groups to …

Cryogen‐free dissolution dynamic nuclear polarization polarizer operating at 3.35 T, 6.70 T, and 10.1 T

JH Ardenkjær‐Larsen, S Bowen… - Magnetic …, 2019 - Wiley Online Library
Purpose A novel dissolution dynamic nuclear polarization (dDNP) polarizer platform is
presented. The polarizer meets a number of key requirements for in vitro, preclinical, and …

Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts

S Jannin, JN Dumez, P Giraudeau… - Journal of Magnetic …, 2019 - Elsevier
Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear
magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of …

Hyperpolarization via dissolution dynamic nuclear polarization: new technological and methodological advances

AC Pinon, A Capozzi, JH Ardenkjær-Larsen - … Resonance Materials in …, 2021 - Springer
Dissolution-DNP is a method to boost liquid-state NMR sensitivity by several orders of
magnitude. The technique consists in hyperpolarizing samples by solid-state dynamic …

Porous functionalized polymers enable generating and transporting hyperpolarized mixtures of metabolites

T El Daraï, SF Cousin, Q Stern, M Ceillier… - Nature …, 2021 - nature.com
Hyperpolarization by dissolution dynamic nuclear polarization (dDNP) has enabled
promising applications in spectroscopy and imaging, but remains poorly widespread due to …

Direct observation of hyperpolarization breaking through the spin diffusion barrier

Q Stern, SF Cousin, F Mentink-Vigier, AC Pinon… - Science …, 2021 - science.org
Dynamic nuclear polarization (DNP) is a widely used tool for overcoming the low intrinsic
sensitivity of nuclear magnetic resonance spectroscopy and imaging. Its practical …