Mucins and their role in shaping the functions of mucus barriers

CE Wagner, KM Wheeler… - Annual review of cell and …, 2018 - annualreviews.org
We review what is currently understood about how the structure of the primary solid
component of mucus, the glycoprotein mucin, gives rise to the mechanical and biochemical …

Passive and active microrheology for biomedical systems

Y Mao, P Nielsen, J Ali - Frontiers in bioengineering and …, 2022 - frontiersin.org
Microrheology encompasses a range of methods to measure the mechanical properties of
soft materials. By characterizing the motion of embedded microscopic particles …

Strategies for optical trapping in biological samples: Aiming at microrobotic surgeons

AI Bunea, J Glückstad - Laser & Photonics Reviews, 2019 - Wiley Online Library
Optical trapping and manipulation of objects down to the Ångstrom level has revolutionized
research at the smallest scales in all natural sciences. The flexibility of optical trapping …

Optical tweezers microrheology: from the basics to advanced techniques and applications

RM Robertson-Anderson - 2018 - ACS Publications
Over the past few decades, microrheology has emerged as a widely used technique to
measure the mechanical properties of soft viscoelastic materials. Optical tweezers offer a …

Co-entangled actin-microtubule composites exhibit tunable stiffness and power-law stress relaxation

SN Ricketts, JL Ross, RM Robertson-Anderson - Biophysical journal, 2018 - cell.com
We use optical tweezers microrheology and fluorescence microscopy to characterize the
nonlinear mesoscale mechanics and mobility of in vitro co-entangled actin-microtubule …

Mechanical shear controls bacterial penetration in mucus

N Figueroa-Morales, L Dominguez-Rubio, TL Ott… - Scientific reports, 2019 - nature.com
Mucus plays crucial roles in higher organisms, from aiding fertilization to protecting the
female reproductive tract. Here, we investigate how anisotropic organization of mucus …

Microrheology with optical tweezers: peaks & troughs

M Tassieri - Current Opinion in Colloid & Interface Science, 2019 - Elsevier
Since their first appearance in the 1970s, optical tweezers have been successfully exploited
for a variety of applications throughout the natural sciences, revolutionising the field of …

Nano‐optical tweezers: Methods and applications for trapping single molecules and nanoparticles

JD Kolbow, NC Lindquist, CT Ertsgaard… - …, 2021 - Wiley Online Library
Optical tweezers were developed in 1970 by Arthur Ashkin as a tool for the manipulation of
micron‐sized particles. Ashkin's original design was then adapted for a variety of purposes …

Unexpected entanglement dynamics in semidilute blends of supercoiled and ring DNA

KR Peddireddy, M Lee, Y Zhou, S Adalbert… - Soft Matter, 2020 - pubs.rsc.org
Blends of polymers of different topologies, such as ring and supercoiled, naturally occur in
biology and often exhibit emergent viscoelastic properties coveted in industry. However, due …

Magnetic wire active microrheology of human respiratory mucus

M Radiom, R Hénault, S Mani, AG Iankovski, X Norel… - Soft Matter, 2021 - pubs.rsc.org
Mucus is a viscoelastic gel secreted by the pulmonary epithelium in the tracheobronchial
region of the lungs. The coordinated beating of cilia moves mucus upwards towards the …