Current landscape of immunotherapy for advanced sarcoma

V Albarrán, ML Villamayor, J Pozas, J Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary The systemic treatment of advanced sarcoma remains challenging.
Conventional chemotherapy and anti-angiogenic agents, even in the most responsive …

Enhancing the potential of immunotherapy in paediatric sarcomas: breaking the immunosuppressive barrier with receptor tyrosine kinase inhibitors

EDG Fleuren, RL Terry, D Meyran, N Omer, JA Trapani… - Biomedicines, 2021 - mdpi.com
Despite aggressive surgery, chemotherapy, and radiotherapy, survival of children and
adolescents and young adults (AYAs) with sarcoma has not improved significantly in the …

The role of immunotherapy in the management of soft tissue sarcomas: current landscape and future outlook

LB Banks, SP D'Angelo - Journal of the National Comprehensive Cancer …, 2022 - jnccn.org
Soft tissue sarcomas (STS) are a subset of sarcoma, a rare group of heterogeneous
malignancies of mesenchymal origin. Current standard of care involves surgical resection …

Real-world efficacy, safety data and predictive clinical parameters for treatment outcomes in advanced soft tissue sarcoma treated with combined immunotherapy and …

S Li, Q Sun, R Bai, Y Wang, H Wang, H Chen, Y Dong - BMC cancer, 2024 - Springer
Background The combination of immunotherapy and antiangiogenic therapy has shown
potential in the treatment of numerous malignant tumors, but limited evidence was available …

Role of Immunotherapy in Sarcomas

S Dalal, KS Shan, NN Thaw Dar, A Hussein… - International Journal of …, 2024 - mdpi.com
Sarcomas are a group of malignancies of mesenchymal origin with a plethora of subtypes.
Given the sheer heterogeneity of various subtypes and the rarity of the disease, the …

Case report: the dissociated response and clinical benefit of primary leiomyosarcoma of the bone treated with penpulimab plus lenvatinib after failed multi-line therapy

B Wang, Y Han, J Liu, X Zhang, H Zhuo… - Frontiers in …, 2023 - frontiersin.org
Leiomyosarcoma occurring in the bone as primary tumor localization is extremely scarce
with limited cases described in the literature, accounting for less than 0.7% of all primary …

[引用][C] 免疫检查点抑制剂在软组织肉瘤中的应用: 现状与展望

薛璐昕, 张志凡, 刘芳岑, 王晓露, 王琴, 刘宝瑞… - 临床肿瘤学杂志, 2023