Central nervous system tumors comprising the primary cancers and brain metastases
remain the most lethal neoplasms and challenging to treat. Substantial evidence points to a …

In eukaryotic cells, AMP-activated protein kinase (AMPK) generally promotes catabolic
pathways that produce ATP and at the same time inhibits anabolic pathways involved in …

Background Many of the current standard therapies employed for the management of
primary malignant brain cancers are largely viewed as palliative, ultimately because these …

Diffuse low-grade and intermediate-grade gliomas (together known as lower grade gliomas,
WHO grade II and III) develop in the supporting glial cells of brain and are the most common …

Glioblastomas continue to rank among the most lethal primary human tumors. Despite
treatment with the most rigorous surgical interventions along with the most optimal …

Glioblastoma remains the most clinically challenging tumor of the CNS, as evidenced by the
dismal change in overall survival over the past 50 years. However, recent advances in high …

The purpose of this review article is to highlight articles and new research regarding the link
between NF-ĸB and several cancers. This review presents the most up-to-date NF-ĸB …

The molecular mechanism for the beneficial effect of fish oil on breast tumor growth is largely
undefined. Using the xenograft model in nude mice, we for the first time report that the fish oil …

The treatment of glioblastoma remains a major challenge for clinicians since these highly
aggressive brain tumors are relatively resistant towards radio-and chemotherapy. The …

NF-κB is a family of important transcription factors involved in many cellular functions, such
as cell survival, proliferation, and stress responses. Many studies indicate that NF-κB is a …