The threats posed by a range of viral and bacterial zoonotic diseases inevitably receive
renewed attention in the wake of global pandemic events due to their overt and devastating …

Liver flukes (Fasciola spp., Opisthorchis spp., Clonorchis sinensis) and blood flukes
(Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in …

Fascioliasis, a serious helminth disease of the livestock population, results from infection
with the parasite Fasciola. Despite the alarming increase in drug resistance, a safe and fully …

Background The tropical liver fluke, Fasciola gigantica causes fasciolosis, an important
disease of humans and livestock. We characterized dynamic transcriptional changes …

In the past decade significant advances in our understanding of liver fluke biology have
been made through in-depth interrogation and analysis of evolving Fasciola hepatica and …

Phosphoglycerate kinase (PGK) is a glycolytic enzyme that is well conserved among the
three domains of life. PGK is usually a monomeric enzyme of about 45 kDa that catalyses …

Simple Summary Chronic wasting in sheep is often related to parasitic infections, especially
to infections with several species of trematodes. Trematodes, or “flukes”, are endoparasites …

Fasciola gigantica and Fasciola hepatica are causative pathogens of fascioliasis, with the
widest latitudinal, longitudinal, and altitudinal distribution; however, among parasites, they …

The tropical liver fluke Fasciola gigantica affects livestock and humans in many Asian
countries, large parts of Africa, and parts of Europe. Despite the public health and economic …

Introduction The only drug effective against the infection caused by Fasciola hepatica or F.
gigantica is triclabendazole (TCBZ), recommended by the WHO and recently approved by …