Genetic studies in mice and humans have revealed the pivotal role of transforming growth
factor-β (TGF-β) signaling during angiogenesis. Mice deficient for various TGF-β signaling …

Endoglin is a transmembrane auxillary receptor for transforming growth factor-β (TGF-β) that
is predominantly expressed on proliferating endothelial cells. Endoglin deficient mice die …

The transforming growth factor β (TGF-β) signaling pathway plays a key role in different
physiological processes such as development, cellular proliferation, extracellular matrix …

Endoglin (CD105) is an integral membrane glycoprotein that serves as a coreceptor for
members of the transforming growth factor-β superfamily of proteins. A major role for …

The cellular and molecular microenvironment of epithelial stem and progenitor cells is
poorly characterized despite well-documented roles in homeostatic tissue renewal, wound …

Epithelial-mesenchymal cell transformation (EMT) is a critical process during development
of the heart valves. Transition of endothelial cells into mesenchymal cells in the …

Endoglin (CD105) is an auxiliary membrane receptor of transforming growth factor beta
(TGF‐β) that interacts with type I and type II TGF‐β receptors and modulates TGF‐β …

Podoplanin is a transmembrane glycoprotein up-regulated in different human tumors,
especially those derived from squamous stratified epithelia (SCCs). Its expression in tumor …

Significance: Proteoglycans have a distinct spatial localization in normal skin and are
essential for the correct structural development, organization, hydration, and functional …

Endoglin is a transmembrane glycoprotein that acts as an auxiliary receptor for transforming
growth factor-β (TGF-β) and modulates cellular responses to this pleiotropic cytokine …