Natural products of pentacyclic triterpenoids: from discovery to heterologous biosynthesis

Y Li, J Wang, L Li, W Song, M Li, X Hua… - Natural Product …, 2023 - pubs.rsc.org
Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …

Lupeol and its derivatives as anticancer and anti-inflammatory agents: Molecular mechanisms and therapeutic efficacy

K Liu, X Zhang, L Xie, M Deng, H Chen, J Song… - Pharmacological …, 2021 - Elsevier
Lupeol is a natural triterpenoid that widely exists in edible fruits and vegetables, and
medicinal plants. In the last decade, a plethora of studies on the pharmacological activities …

Neuroprotective effect of quercetin against the detrimental effects of LPS in the adult mouse brain

A Khan, T Ali, SU Rehman, MS Khan, SI Alam… - Frontiers in …, 2018 - frontiersin.org
Chronic neuroinflammation is responsible for multiple neurodegenerative diseases, such as
Alzheimer's disease, Parkinson's disease, and Huntington's disease. Lipopolysaccharide …

Roles and mechanisms of gut microbiota in patients with Alzheimer's disease

S Wu, X Liu, R Jiang, X Yan, Z Ling - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common age-related progressive neurodegenerative
disease, characterized by a decline in cognitive function and neuronal loss, and is caused …

Role of endogenous lipopolysaccharides in neurological disorders

M Kalyan, AH Tousif, S Sonali, C Vichitra, T Sunanda… - Cells, 2022 - mdpi.com
Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …

A comprehensive review of natural compounds for wound healing: targeting bioactivity perspective

XT Trinh, NV Long, LT Van Anh, PT Nga… - International Journal of …, 2022 - mdpi.com
Wound healing is a recovering process of damaged tissues by replacing dysfunctional
injured cellular structures. Natural compounds for wound treatment have been widely used …

Neurological enhancement effects of melatonin against brain injury-induced oxidative stress, neuroinflammation, and neurodegeneration via AMPK/CREB signaling

SU Rehman, M Ikram, N Ullah, SI Alam, HY Park… - Cells, 2019 - mdpi.com
Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases.
Repeated concussion is becoming a serious public health issue with uncontrollable adverse …

Melatonin rescue oxidative stress-mediated neuroinflammation/neurodegeneration and memory impairment in scopolamine-induced amnesia mice model

T Muhammad, T Ali, M Ikram, A Khan, SI Alam… - Journal of Neuroimmune …, 2019 - Springer
Cognitive decline and memory impairment induced by oxidative brain damage are the
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …

[HTML][HTML] A critical review on quercetin bioflavonoid and its derivatives: scope, synthesis, and biological applications with future prospects

S Dhanaraj - Arabian Journal of Chemistry, 2023 - Elsevier
Lifestyle is an important factor in health, and researchers are trying to see the adverse effect
on human health of a change in lifestyle. Many people follow unhealthy lifestyles, which …

Neuroprotective effect of fisetin against amyloid-beta-induced cognitive/synaptic dysfunction, neuroinflammation, and neurodegeneration in adult mice

A Ahmad, T Ali, HY Park, H Badshah, SU Rehman… - Molecular …, 2017 - Springer
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease and
is characterized pathologically by the accumulation of amyloid beta (Aβ) and the …