M Zoli - European Biophysics Journal, 2022 - Springer
Nucleic acids' physical properties have been investigated by theoretical methods based both on fully atomistic representations and on coarse-grained models, eg, the worm-like …
Motivation The two strands of the DNA double helix locally and spontaneously separate and recombine in living cells due to the inherent thermal DNA motion. This dynamics results in …
A Basov, A Dorohova, V Malyshko, A Moiseev… - International Journal of …, 2023 - mdpi.com
The influence of a single 2H/1H replacement on the frequency generation of different-size bubbles in the human interferon alpha-17 gene (IFNA17) under various energies was …
In this study we derive analytically the equilibrium melting probabilities for basepairs of a DNA molecule with a defect site. We assume that the defect is characterized by a change in …
MI Drobotenko, AA Svidlov, АA Dorohova… - Journal of …, 2023 - Taylor & Francis
The studies were carried out by the mathematical modeling of DNA mechanical deformations. Numerical calculations done for the interferon alpha 17 gene, which consists …
M Zoli - Physica Scripta, 2024 - iopscience.iop.org
Considering a one dimensional mesoscopic model for DNA, we focus on the upper bound for the base pair fluctuations, a relevant parameter in computer simulations for which …
There is evidence that DNA breathing (spontaneous opening of the DNA strands) plays a relevant role in the interactions of DNA with other molecules, and in particular in the …
Understanding the inherent timescales of large bubbles in DNA is critical to a thorough comprehension of its physicochemical characteristics, as well as their potential role on helix …
We investigated the melting transition of deoxyribonucleic acid (DNA) embedded in a Langevin fluctuation–dissipation thermal bath. Torsional effects were taken into …