Zebrafish (Danio rerio) is extensively used in research; however the mechanisms that
control this species sex determination are still poorly understood. In the latest decades, it …

Thyroid hormones (THs) are well-known regulators of development and metabolism in
vertebrates. There is increasing evidence that THs are also involved in gonadal …

Identification of thyroid disrupting chemicals (TDCs), one of the most studied types of
endocrine disruptors (EDs), is required according to EU regulations on industrial chemicals …

Thyroid hormone system disrupting compounds are considered potential threats for human
and environmental health. Multiple adverse outcome pathways (AOPs) for thyroid hormone …

Endocrine disruptors (EDs) are synthetic or natural chemical molecules occurring in
environment that have the potential to impart adverse effects on homeostasis of endocrine …

The objective of this review was to summarize and discuss the effects of Polybrominated
diphenyl ethers (PBDEs) on thyroid and reproduction systems in fish. We reviewed the …

Fish sex ratio (SR) is an endpoint potentially indicating both endocrine activity and adversity,
essential elements for identifying Endocrine Disrupting Chemicals (EDCs) as required by …

Persistent organic pollutants (POPs) are ubiquitous environmental contaminants that are not
readily degraded in the environment. They are typically lipophilic, bioaccumulating in tissues …

Thyroid hormones (THs) play important roles in the regulation of many biological processes
of vertebrates, such as growth, metabolism, morphogenesis and reproduction. An increasing …

The strobilurin fungicide azoxystrobin (AZO) can induce adverse effects in aquatic
organisms, but data are lacking on endpoints associated with sexual development and …