Machine learning approach to enhance the performance of MNP-labeled lateral flow immunoassay

W Yan, K Wang, H Xu, X Huo, Q Jin, D Cui - Nano-Micro Letters, 2019 - Springer
The use of magnetic nanoparticle (MNP)-labeled immunochromatography test strips (ICTSs)
is very important for point-of-care testing (POCT). However, common diagnostic methods …

Analytical platform with selectable assay parameters based on three functions of magnetic nanoparticles: demonstration of highly sensitive rapid quantitation of …

VA Bragina, SL Znoyko, AV Orlov… - Analytical …, 2019 - ACS Publications
Many immunoassay platforms require time-and labor-consuming tuning of parameters for
operation in complex mediums (food, whole blood, etc.), but no universal method has been …

Rapid dry-reagent immunomagnetic biosensing platform based on volumetric detection of nanoparticles on 3D structures

AV Orlov, VA Bragina, MP Nikitin, PI Nikitin - Biosensors and Bioelectronics, 2016 - Elsevier
A dry-reagent immunomagnetic (DRIM) biosensing platform is developed for rapid high-
precision quantitative analyses for in vitro diagnostics. The platform combines the …

Multiplex label-free biosensor for detection of autoantibodies in human serum: Tool for new kinetics-based diagnostics of autoimmune diseases

AV Orlov, AV Pushkarev, SL Znoyko… - Biosensors and …, 2020 - Elsevier
A multiplex label-free biosensor is developed for diagnostics of autoimmune diseases by
highly sensitive measuring in human serum both critical characteristics of autoantibody …

Magnetic immunoassay for detection of staphylococcal toxins in complex media

AV Orlov, JA Khodakova, MP Nikitin… - Analytical …, 2013 - ACS Publications
Method of highly sensitive registration of magnetic nanoparticles by their nonlinear
magnetization is used in a novel sandwich-type immunoassay for detection of …

Multiplex label-free kinetic characterization of antibodies for rapid sensitive cardiac troponin I detection based on functionalized magnetic nanotags

AV Orlov, JA Malkerov, DO Novichikhin… - International Journal of …, 2022 - mdpi.com
Express and highly sensitive immunoassays for the quantitative registration of cardiac
troponin I (cTnI) are in high demand for early point-of-care differential diagnosis of acute …

Ultrasensitive quantitative detection of small molecules with rapid lateral-flow assay based on high-affinity bifunctional ligand and magnetic nanolabels

SL Znoyko, AV Orlov, AV Pushkarev… - Analytica Chimica …, 2018 - Elsevier
An ultrasensitive lateral-flow assay is developed for rapid quantitative detection of small
molecules on-site. The conceptual novelty, which transfers lateral-flow assays to the …

Nanobiosensing based on optically selected antibodies and superparamagnetic labels for rapid and highly sensitive quantification of polyvalent hepatitis B surface …

VA Bragina, AV Orlov, SL Znoyko, AV Pushkarev… - Analytical …, 2021 - pubs.rsc.org
Hepatitis B surface antigen (HBsAg) is the most clinically relevant serological marker of
hepatitis B virus (HBV) infection. Its detection in blood is extremely important for identification …

[图书][B] Rabies: scientific basis of the disease and its management

AR Fooks, AC Jackson - 2020 - books.google.com
Rabies: Basis of the Disease and Its Management, Fourth Edition is an authoritative
reference on the current status of rabies, including the virological, clinical, and public health …

Highly reproducible and sensitive detection of mycotoxins by label-free biosensors

AV Orlov, AG Burenin, NG Massarskaya… - Sensors and actuators B …, 2017 - Elsevier
Enhancement of sensitivity and reproducibility of measuring the concentration of small
molecules (haptens) is crucially important for a wide variety of applications. The …