Intracellular delivery is a key step in biological research and has enabled decades of
biomedical discoveries. It is also becoming increasingly important in industrial and medical …

Satellite cells, the quintessential skeletal muscle stem cells, reside in a specialized local
environment whose anatomy changes dynamically during tissue regeneration. The plasticity …

The CRISPR/Cas9 genome-editing platform is a promising technology to correct the genetic
basis of hereditary diseases. The versatility, efficiency and multiplexing capabilities of the …

Mesoangioblasts are stem/progenitor cells derived from a subset of pericytes found in
muscle that express alkaline phosphatase. They have been shown to ameliorate the …

Muscular dystrophies are a heterogeneous group of genetic diseases, characterized by
progressive degeneration of skeletal and cardiac muscle. Despite the intense investigation …

В книге популярно излагаются методы футурологии и результаты, достигаемые
благодаря этим методам. Основная идея книги заключается в том, что главным …

Intra‐arterial transplantation of mesoangioblasts proved safe and partially efficacious in
preclinical models of muscular dystrophy. We now report the first‐in‐human, exploratory …

Skeletal muscle is the largest organ of human body with several important roles in everyday
movement and metabolic homeostasis. The limited ability of small animal models of muscle …

Background Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular
childhood disorder that causes progressive muscle weakness and degeneration and results …

Skeletal muscle is a complex tissue composed of multinucleated myofibers responsible for
force generation that are supported by multiple cell types. Many severe and lethal disorders …