Embryonic and larval zebrafish models for the discovery of new bioactive compounds against TB
TB is a world health challenge the treatment of which is impacted by the rise of drug-
resistant strains. Thus, there is an urgent need for new antitubercular compounds and novel …
resistant strains. Thus, there is an urgent need for new antitubercular compounds and novel …
[HTML][HTML] Breaking barriers: The potential of nanosystems in antituberculosis therapy
CSC Canales, JIM Cazorla, RMM Cazorla… - Bioactive Materials, 2024 - Elsevier
Tuberculosis (TB), caused by Mycobacterium tuberculosis, continues to pose a significant
threat to global health. The resilience of TB is amplified by a myriad of physical, biological …
threat to global health. The resilience of TB is amplified by a myriad of physical, biological …
Mycobacterium tuberculosis β-lactamase variant reduces sensitivity to ampicillin/avibactam in a zebrafish-Mycobacterium marinum model of tuberculosis
I van Alen, MA Aguirre García, JJ Maaskant, CP Kuijl… - Scientific reports, 2023 - nature.com
The β-lactamase of Mycobacterium tuberculosis, BlaC, hydrolyzes β-lactam antibiotics,
hindering the use of these antibiotics for the treatment of tuberculosis. Inhibitors, such as …
hindering the use of these antibiotics for the treatment of tuberculosis. Inhibitors, such as …
Expanding the field of view–a simple approach for interactive visualisation of electron microscopy data
J Wohlmann - Journal of Cell Science, 2024 - journals.biologists.com
The unparalleled resolving power of electron microscopy is both a blessing and a curse. At
30,000× magnification, 1 µm corresponds to 3 cm in the image and the field of view is only a …
30,000× magnification, 1 µm corresponds to 3 cm in the image and the field of view is only a …
Current developments and prospects of the antibiotic delivery systems
K Kharga, S Jha, T Vishwakarma… - Critical Reviews in …, 2024 - Taylor & Francis
Antibiotics have remained the cornerstone for the treatment of bacterial infections ever since
their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria …
their discovery in the twentieth century. The uproar over antibiotic resistance among bacteria …
Review of inhalable nanoparticles for the pulmonary delivery of anti-tuberculosis drugs
S Ramachandran, P Prakash, N Mohtar… - Pharmaceutical …, 2023 - Taylor & Francis
Tuberculosis is an airborne disease caused by the pathogen, Mycobacterium tuberculosis,
which predominantly affects the lungs. World Health Organization (WHO) has reported that …
which predominantly affects the lungs. World Health Organization (WHO) has reported that …