We are in a phase of unprecedented progress in identifying genetic loci that cause variation
in traits ranging from growth and fitness in simple organisms to disease in humans …

Phenotypic plasticity can serve as a stepping stone towards adaptation. Recently, studies
have shown that gene expression contributes to emergent stress responses such as thermal …

Pleiotropy is the well-established phenomenon of a single gene affecting multiple traits. It
has long played a central role in theoretical, experimental, and clinical research in genetics …

There is considerable interest in the occurrence and molecular mechanisms of phenotypic
plasticity and genotype-by-environment interactions (G× E) in plant populations. The …

Introduction Variation in an individual's response to environmental factors is likely to
influence susceptibility to complex human diseases. The genetic basis of such variation is …

Variation in gene expression is an important mechanism underlying susceptibility to
complex disease. The simultaneous genome-wide assay of gene expression and genetic …

Phenotypic plasticity, the expression of multiple phenotypes from one genome, is a
widespread adaptation to short-term environmental fluctuations, but whether it facilitates …

Abstract Background The nematode Caenorhabditis elegans is a major model organism in
laboratory biology. Very little is known, however, about its ecology, including where it …

Developmental plasticity refers to the property by which the same genotype produces
distinct phenotypes depending on the environmental conditions under which development …

Motivation: R/qtl is free and powerful software for mapping and exploring quantitative trait
loci (QTL). R/qtl provides a fully comprehensive range of methods for a wide range of …