Decellularization in tissue engineering and regenerative medicine: evaluation, modification, and application methods

A Neishabouri, A Soltani Khaboushan… - … in bioengineering and …, 2022 - frontiersin.org
Reproduction of different tissues using scaffolds and materials is a major element in
regenerative medicine. The regeneration of whole organs with decellularized extracellular …

Mesenchymal stem cell perspective: cell biology to clinical progress

MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Tissue-engineered grafts from human decellularized extracellular matrices: a systematic review and future perspectives

A Porzionato, E Stocco, S Barbon, F Grandi… - International journal of …, 2018 - mdpi.com
Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

A review of cellularization strategies for tissue engineering of whole organs

ME Scarritt, NC Pashos, BA Bunnell - Frontiers in bioengineering and …, 2015 - frontiersin.org
With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

ECM in differentiation: a review of matrix structure, composition and mechanical properties

A Padhi, AS Nain - Annals of biomedical engineering, 2020 - Springer
Stem cell regenerative potential owing to the capacity to self-renew as well as differentiate
into other cell types is a promising avenue in regenerative medicine. Stem cell niche not …

Controlling stem cell behavior with decellularized extracellular matrix scaffolds

G Agmon, KL Christman - Current Opinion in Solid State and Materials …, 2016 - Elsevier
Decellularized tissues have become a common regenerative medicine platform with multiple
materials being researched in academic laboratories, tested in animal studies, and used …

Acellular human lung scaffolds to model lung disease and tissue regeneration

SE Gilpin, DE Wagner - European Respiratory Review, 2018 - Eur Respiratory Soc
Recent advances in whole lung bioengineering have opened new doors for studying lung
repair and regeneration ex vivo using acellular human derived lung tissue scaffolds …

Overview of the development, applications, and future perspectives of decellularized tissues and organs

N Nakamura, T Kimura, A Kishida - ACS biomaterials science & …, 2017 - ACS Publications
Decellularized tissues, in which the extracellular matrix is isolated, have broad applications
as implantable biomaterials and/or biological scaffolds for tissue repair, and show good …

Renal regeneration: the role of extracellular matrix and current ECM‐based tissue engineered strategies

R Sobreiro‐Almeida, R Quinteira… - Advanced healthcare …, 2021 - Wiley Online Library
Natural extracellular matrices (ECM) are currently being studied as an alternative source for
organ transplantation or as new solutions to treat kidney injuries, which can evolve to end …