Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish

JR Lenkowski, PA Raymond - Progress in retinal and eye research, 2014 - Elsevier
Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related
neurogenesis allows a vigorous regenerative response to damage, and fish can regenerate …

Proliferative vitreoretinopathy: current and emerging treatments

A Sadaka, GP Giuliari - Clinical ophthalmology, 2012 - Taylor & Francis
Proliferative vitreoretinopathy is a disease process that follows the proliferation of ectopic
cell sheets in the vitreous and/or periretinal area, causing periretinal membrane formation …

Proliferative vitreoretinopathy after eye injuries: an overexpression of growth factors and cytokines leading to a retinal keloid

F Morescalchi, S Duse, E Gambicorti… - Mediators of …, 2013 - Wiley Online Library
Eye injury is a significant disabling worldwide health problem. Proliferative Vitreoretinopathy
(PVR) is a common complication that develops in up to 40–60% of patients with an open …

Is neutralizing vitreal growth factors a viable strategy to prevent proliferative vitreoretinopathy?

S Pennock, LJ Haddock, D Eliott, S Mukai… - Progress in retinal and …, 2014 - Elsevier
Proliferative vitreoretinopathy (PVR) is a blinding disorder that occurs in eyes with
rhegmatogenous retinal detachment and in eyes that have recently undergone retinal …

[HTML][HTML] Mechanisms of epithelial-mesenchymal transition in proliferative vitreoretinopathy

S Yang, H Li, M Li, F Wang - Discovery medicine, 2015 - discoverymedicine.com
Proliferative vitreoretinopathy (PVR) is a blinding disease characterized by the formation of
epiretinal membranes through the wound repair process. Though the mechanisms of PVR …

TGF-β participates choroid neovascularization through Smad2/3-VEGF/TNF-α signaling in mice with Laser-induced wet age-related macular degeneration

X Wang, W Ma, S Han, Z Meng, L Zhao, Y Yin… - Scientific Reports, 2017 - nature.com
Choroidal neovascularization (CNV) is the most severe complication in Age-related macular
degeneration (AMD) and the most common cause of irreversible blindness in the elderly in …

Inflammatory mediators of proliferative vitreoretinopathy: hypothesis and review

Y Dai, C Dai, T Sun - International ophthalmology, 2020 - Springer
Purpose To review the role of inflammatory mediators in proliferative vitreoretinopathy (PVR)
development and the current treatment for PVR prevention. Methods A PubMed search was …

Anti-angiogenic and anti-scarring dual action of an anti-fibroblast growth factor 2 aptamer in animal models of retinal disease

Y Matsuda, Y Nonaka, S Futakawa, H Imai… - … Therapy-Nucleic Acids, 2019 - cell.com
Currently approved therapies for age-related macular degeneration (AMD) are inhibitors
against vascular endothelial growth factor (VEGF), which is a major contributor to the …

Experimental models to study epithelial-mesenchymal transition in proliferative vitreoretinopathy

A Datlibagi, A Zein-El-Din, M Frohly… - International journal of …, 2023 - mdpi.com
Proliferative vitreoretinal diseases (PVDs) encompass proliferative vitreoretinopathy (PVR),
epiretinal membranes, and proliferative diabetic retinopathy. These vision-threatening …

Role of decorin in the lens and ocular diseases

E Kubo, S Shibata, T Shibata, H Sasaki, DP Singh - Cells, 2022 - mdpi.com
Decorin is an archetypal member of the small leucine-rich proteoglycan gene family and is
involved in various biological functions and many signaling networks, interacting with extra …