Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain

MP Jurkowski, L Bettio, E K. Woo, A Patten… - Frontiers in cellular …, 2020 - frontiersin.org
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …

Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia

N Takahashi, T Sakurai, KL Davis, JD Buxbaum - Progress in neurobiology, 2011 - Elsevier
Multiple lines of evidence in schizophrenia, from brain imaging, studies in postmortem
brains, and genetic association studies, have implicated oligodendrocyte and myelin …

[HTML][HTML] Aberrant lipid metabolism in the forebrain niche suppresses adult neural stem cell proliferation in an animal model of Alzheimer's disease

LK Hamilton, M Dufresne, SE Joppé, S Petryszyn… - Cell stem cell, 2015 - cell.com
Lipid metabolism is fundamental for brain development and function, but its roles in normal
and pathological neural stem cell (NSC) regulation remain largely unexplored. Here, we …

Stem cells for ischemic brain injury: a critical review

TC Burns, CM Verfaillie, WC Low - Journal of Comparative …, 2009 - Wiley Online Library
No effective therapy is currently available to promote recovery following ischemic stroke.
Stem cells have been proposed as a potential source of new cells to replace those lost due …

NeuroD1 induces terminal neuronal differentiation in olfactory neurogenesis

C Boutin, O Hardt, A De Chevigny… - Proceedings of the …, 2010 - National Acad Sciences
After their generation and specification in periventricular regions, neuronal precursors
maintain an immature and migratory state until their arrival in the respective target structures …

Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson's disease

L Cova, MT Armentero, E Zennaro, C Calzarossa… - Brain research, 2010 - Elsevier
Stimulation of endogenous repair in neurodegenerative diseases, such as Parkinson's
disease (PD), appears to be a novel and promising therapeutic application of stem cells …

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

SA Van Den Berge, ME Van Strien, JA Korecka… - Brain, 2011 - academic.oup.com
There are many indications that neurogenesis is impaired in Parkinson's disease, which
might be due to a lack of dopamine in the subventricular zone. An impairment in …

The path from the choroid plexus to the subventricular zone: go with the flow!

AM Falcão, F Marques, A Novais, N Sousa… - Frontiers in cellular …, 2012 - frontiersin.org
In adult mammals, under physiological conditions, neurogenesis, the process of generating
new functional neurons from precursor cells, occurs mainly in two brain areas: the …

Dynamical systems model of RNA velocity improves inference of single-cell trajectory, pseudo-time and gene regulation

R Liu, AO Pisco, E Braun, S Linnarsson… - Journal of Molecular …, 2022 - Elsevier
Recent development in inferring RNA velocity from single-cell RNA-seq opens up exciting
new vista into developmental lineage and cellular dynamics. However, the estimated …

From neurotransmitters to neurotrophic factors to neurogenesis

T Hagg - The Neuroscientist, 2009 - journals.sagepub.com
New neurons continue to be produced in adult mammals, including humans, predominantly
in the anterior subventricular zone of the lateral ventricle and the subgranular zone of the …