Psychiatric disorders are complex multifactorial disorders involving chronic alterations in
neural circuit structure and function. While genetic factors play a role in the etiology of …

Schizophrenia is considered primarily as a cognitive disorder. However, functional
outcomes in schizophrenia are limited by the lack of effective pharmacological and …

Schizophrenia is a major psychiatric disorder that lacks a unifying neuropathology, while
currently available pharmacological treatments provide only limited benefits to many …

The prefrontal cortex (PFC) and its connections with other brain areas are crucial for
cognitive function. Cognitive impairments are one of the core symptoms associated with …

One hundred years after its conceptual definition as 'Dementia Praecox'by Emil Kraepelin,
schizophrenia is still a serious psychiatric illness that affects young adults and leads to …

Biomarkers which predict response to atypical antipsychotic drugs (AAPDs) increases their
benefit/risk ratio. We sought to identify common variants in genes which predict response to …

Nonrandom chromosomal conformations, including promoter–enhancer loopings that
bypass kilobases or megabases of linear genome, provide a crucial layer of transcriptional …

Methamphetamine (METH)-use disorder (MUD) is a very serious, potentially lethal,
biopsychosocial disease. Exposure to METH causes long-term changes to brain regions …

Schizophrenia (SZ) is a devastating complex genetic mental condition that is heterogeneous
in terms of clinical etiologies, symptoms, and outcomes. Despite decades of postmortem …

Background: Emerging evidence suggests that epigenetic mechanisms are involved in
different brain functions such as the development of the nervous system and normal …