CircRNA and lncRNA-encoded peptide in diseases, an update review

Q Yi, J Feng, W Lan, H Shi, W Sun, W Sun - Molecular Cancer, 2024 - Springer
Abstract Non-coding RNAs (ncRNAs), including circular RNAs (circRNAs) and long non-
coding RNAs (lncRNAs), are unique RNA molecules widely identified in the eukaryotic …

LncRNA-encoded peptides in cancer

Y Zhang - Journal of Hematology & Oncology, 2024 - Springer
Long non-coding RNAs (lncRNAs), once considered transcriptional noise, have emerged as
critical regulators of gene expression and key players in cancer biology. Recent …

Current understanding of functional peptides encoded by lncRNA in cancer

H Tian, L Tang, Z Yang, Y Xiang, Q Min, M Yin… - Cancer Cell …, 2024 - Springer
Dysregulated gene expression and imbalance of transcriptional regulation are typical
features of cancer. RNA always plays a key role in these processes. Human transcripts …

A Mammalian Conserved Circular RNA CircLARP1B Regulates Hepatocellular Carcinoma Metastasis and Lipid Metabolism

J Li, X Wang, L Shi, B Liu, Z Sheng, S Chang… - Advanced …, 2024 - Wiley Online Library
Circular RNAs (circRNAs) have emerged as crucial regulators in physiology and human
diseases. However, evolutionarily conserved circRNAs with potent functions in cancers are …

Enlightening the path to NSCLC biomarkers: Utilizing the power of XAI-guided deep learning

K Dwivedi, A Rajpal, S Rajpal, V Kumar… - Computer Methods and …, 2024 - Elsevier
Abstract Background and Objective The early diagnosis of Non-small cell lung cancer
(NSCLC) is of prime importance to improve the patient's survivability and quality of life …

NAP-seq reveals multiple classes of structured noncoding RNAs with regulatory functions

S Liu, J Huang, J Zhou, S Chen, W Zheng, C Liu… - Nature …, 2024 - nature.com
Up to 80% of the human genome produces “dark matter” RNAs, most of which are
noncapped RNAs (napRNAs) that frequently act as noncoding RNAs (ncRNAs) to modulate …

Higher gestational weight gain delays wound healing and reduces expression of long non‐coding RNA KLRK1‐AS1 in neonatal endothelial progenitor cells

E Weiss, A Schrüfer, C Tocantins… - The Journal of …, 2023 - Wiley Online Library
High gestational weight gain (GWG) is a cardiovascular risk factor and may disturb neonatal
endothelial function. Long non‐coding RNAs (lncRNAs) regulate gene expression …

Subcellular localization and relevant mechanisms of human cancer‐related micropeptides

J Deng, W Xu, Y Jie, Y Chong - The FASEB Journal, 2023 - Wiley Online Library
Rapid advances in high‐quality sequencing and bioinformatics have invalidated the
argument that noncoding RNAs (ncRNAs) are junk transcripts that do not encode proteins …

Integrative multi-omics analysis reveals the translational landscape of the plant-parasitic nematode Meloidogyne incognita

Z Zhu, D Bo, C Xie, D Dai, D Peng, M Sun… - Communications …, 2025 - nature.com
Root-knot nematodes (RKNs) of the genus Meloidogyne pose the most significant threats to
global food security due to their destructive nature as plant-parasitic nematodes. Although …

Prevalence of and gene regulatory constraints on transcriptional adaptation in single cells

IA Mellis, ME Melzer, N Bodkin, Y Goyal - Genome biology, 2024 - Springer
Background Cells and tissues have a remarkable ability to adapt to genetic perturbations via
a variety of molecular mechanisms. Nonsense-induced transcriptional compensation, a form …