Though vesicular delivery systems have been widely explored and reviewed, no
comprehensive review exists that covers their development from the inception of the concept …

Small interfering RNA (siRNA) has gained attention as a potential therapeutic reagent due to
its ability to inhibit specific genes in many genetic diseases. For many years, studies of …

Cancer is a disease that has been the focus of scientific research and discovery and
continues to remain so. Polo-like kinases (PLKs) are basically serine/threonine kinase …

This study aims to investigate the regulative effects of microRNA‐451a (miR‐451a) on cell
proliferation and sensitivity to tamoxifen in breast cancer cells. In cell culture experiments …

BACKGROUND: Liver carcinoma is a major cause of cancer-related death worldwide. Up to
date, the mechanisms of liver cancerigenesis and development have not been fully …

Although multimodal therapies including surgery, chemotherapy, and radiotherapy have
improved clinical outcomes of patients with bone and soft tissue sarcomas, the prognosis of …

Considering the subdued efficacy of a single therapeutic modality in successful treatment of
cancer, co-operative inhibition of cancer progression employing a combination of two or …

Therapeutics, based on small interfering RNA (siRNA), have demonstrated tremendous
potential for treating cancer. However, issues such as non-specific targeting, premature …

RNA interference has emerged as an innovative technology for gene silencing that
degrades mRNAs complementary to the antisense strands of double-stranded, short …

Liver cancer results in enormous human toll worldwide. Over the years, various
chemotherapeutic entities have been employed for treatment of advanced HCC; however …