Intracellular bacterial infections: a challenge for developing cellular mediated immunity vaccines for farmed fish

HM Munang'andu - Microorganisms, 2018 - mdpi.com
Aquaculture is one of the most rapidly expanding farming systems in the world. Its rapid
expansion has brought with it several pathogens infecting different fish species. As a result …

Transcriptome analysis of immune-and iron-related genes after Francisella noatunensis subsp. orientalis infection in Nile tilapia (Oreochromis niloticus)

S Maekawa, T Pulpipat, PC Wang, SC Chen - Fish & Shellfish Immunology, 2021 - Elsevier
Francisella noatunensis subsp. orientalis (Fno) is a gram-negative intracellular bacterium
identified in many fish species worldwide, including cultured Nile tilapia (Oreochromis …

An initial evaluation of fishmeal replacement with soy protein sources on growth and immune responses of burbot (Lota lota maculosa)

TJ Bruce, LP Oliver, J Ma, BC Small, RW Hardy… - Aquaculture, 2021 - Elsevier
Burbot (Lota lota maculosa) are the only freshwater member of the cod family (Gadidae) and
potentially a new species for aquaculture production. This “freshwater cod” species could …

Dissection of Francisella-host cell interactions in Dictyostelium discoideum

EO Lampe, Y Brenz, L Herrmann… - Applied and …, 2016 - Am Soc Microbiol
Francisella bacteria cause severe disease in both vertebrates and invertebrates and include
one of the most infectious human pathogens. Mammalian cell lines have mainly been used …

Larva of greater wax moth Galleria mellonella is a suitable alternative host for the fish pathogen Francisella noatunensis subsp. orientalis

WAS Djainal, K Shahin, M Metselaar, A Adams… - BMC microbiology, 2020 - Springer
Background Francisella noatunensis subsp. orientalis (Fno) is the etiological agent of
francisellosis in cultured warm water fish, such as tilapia. Antibiotics are administered to treat …

[HTML][HTML] Disentangling the immune response and host-pathogen interactions in Francisella noatunensis infected Atlantic cod

MH Solbakken, S Jentoft, T Reitan, H Mikkelsen… - … and Physiology Part D …, 2019 - Elsevier
The genetic repertoire underlying teleost immunity has been shown to be highly variable. A
rare example is Atlantic cod and its relatives Gadiformes that lacks a hallmark of vertebrate …

[HTML][HTML] Whole transcriptome analysis of the Atlantic cod vaccine response reveals subtle changes in adaptive immunity

MH Solbakken, S Jentoft, T Reitan, H Mikkelsen… - … and Physiology Part D …, 2019 - Elsevier
Atlantic cod has lost the Major Histocompatibility complex class II pathway–central to
pathogen presentation, humoral response and immunity. Here, we investigate the …

[HTML][HTML] Immunomodulatory properties of Concholepas concholepas hemocyanin against francisellosis in a zebrafish model

L Lagos, JI Tandberg, MI Becker… - Fish & Shellfish …, 2017 - Elsevier
The development of vaccines for aquaculture has been an important milestone in providing
a continuous and sustainable production. Most of the vaccines currently on the market for …

Protection and antibody reactivity in lumpsucker (Cyclopterus lumpus L.) following vaccination against Pasteurella sp.

RM Ellul, J Bulla, E Brudal, D Colquhoun… - Fish & shellfish …, 2019 - Elsevier
Two monovalent vaccines against pasteurellosis were developed and tested for efficacy
using a previously established bath challenge model. High levels of specific antibodies were …

Francisella noatunensis subsp. noatunensis invades, survives and replicates in Atlantic cod cells

KR Bakkemo, H Mikkelsen, A Johansen… - Diseases of Aquatic …, 2016 - int-res.com
Systemic infection caused by the facultative intracellular bacterium Francisella noatunensis
subsp. noatunensis remains a disease threat to Atlantic cod Gadus morhua L. Future …