Biomimetic porous scaffolds for bone tissue engineering

S Wu, X Liu, KWK Yeung, C Liu, X Yang - Materials Science and …, 2014 - Elsevier
Increased use of reconstruction procedures in orthopedics, due to trauma, tumor, deformity,
degeneration and an aging population, has caused a blossom, not only in surgical …

Long-acting PLGA microspheres: advances in excipient and product analysis toward improved product understanding

B Wan, Q Bao, D Burgess - Advanced drug delivery reviews, 2023 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) microspheres are a sustained-release drug delivery
system with several successful commercial products used for the treatment of a variety of …

Drug release from in situ forming implants and advances in release testing

X Wang, DJ Burgess - Advanced Drug Delivery Reviews, 2021 - Elsevier
In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Challenges and Complications of Poly(lactic-co-glycolic acid)-Based Long-Acting Drug Product Development

YW Lim, WS Tan, KL Ho, AR Mariatulqabtiah… - Pharmaceutics, 2022 - mdpi.com
Poly (lactic-co-glycolic acid)(PLGA) is one of the preferred polymeric inactive ingredients for
long-acting parenteral drug products that are constituted of complex formulations. Despite …

[HTML][HTML] Porous silicon embedded in a thermoresponsive hydrogel for intranasal delivery of lipophilic drugs to treat rhinosinusitis

S Bakshi, P Pandey, Y Mohammed, J Wang… - Journal of Controlled …, 2023 - Elsevier
Intranasal delivery is the most preferred route of drug administration for treatment of a range
of nasal conditions including chronic rhinosinusitis (CRS), caused by an infection and …

In vitro dissolution testing strategies for nanoparticulate drug delivery systems: recent developments and challenges

J Shen, DJ Burgess - Drug delivery and translational research, 2013 - Springer
Nanoparticulate systems have emerged as prevalent drug delivery systems over the past
few decades. These delivery systems (such as liposomes, emulsions, nanocrystals, and …

Recent progress in drug release testing methods of biopolymeric particulate system

Y Kim, EJ Park, TW Kim, DH Na - Pharmaceutics, 2021 - mdpi.com
Biopolymeric microparticles have been widely used for long-term release formulations of
short half-life chemicals or synthetic peptides. Characterization of the drug release from …

Accelerated in-vitro release testing methods for extended-release parenteral dosage forms

J Shen, DJ Burgess - Journal of Pharmacy and Pharmacology, 2012 - academic.oup.com
Objectives This review highlights current methods and strategies for accelerated in-vitro
drug release testing of extended-release parenteral dosage forms such as polymeric …

Photolabile linkers: exploiting labile bond chemistry to control mode and rate of hydrogel degradation and protein release

PJ LeValley, R Neelarapu, BP Sutherland… - Journal of the …, 2020 - ACS Publications
Photolabile moieties have been utilized in applications ranging from peptide synthesis and
controlled protein activation to tunable and dynamic materials. The photochromic properties …

[HTML][HTML] An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants

Z Li, H Mu, SW Larsen, H Jensen… - International Journal of …, 2021 - Elsevier
In situ forming implants are exposed to an extracellular matrix resembling a gel rather than
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …