Breast cancer is the most common cancer among females worldwide. Several
epidemiological studies suggested the inverse correlation between the intake of vegetables …

Indole-3-carbinol (I3C) is produced by members of the family Cruciferae, and particularly
members of the genus Brassica (eg, cabbage, radishes, cauliflower, broccoli, Brussels …

This article reviews the mechanisms by which glucosinolate breakdown products are
thought to inhibit carcinogenesis. It describes how isothiocyanates, thiocyanates, nitriles …

During the course of oncogenesis and tumor progression, cancer cells constitutively
upregulate signaling pathways relevant to cell proliferation and survival as a strategy to …

Indole-3-carbinol (I3C) conjugates are phytochemicals expressed in brassica vegetables
and have been associated with the anticancer activities of vegetable consumption. I3C and …

Brassica vegetable consumption (eg, Chinese cabbage) provides isothiocyanates (ITC) and
other glucosinolate derivatives capable of inducing Phase II enzymes [eg, glutathione S …

Mounting preclinical and clinical evidence indicate that indole-3-carbinol (I3C), a key
bioactive food component in cruciferous vegetables, has multiple anticarcinogenic and …

As our understanding of the development of cancer and the complex signalling mechanisms
involved improves, we are beginning to appreciate the enormous potential for intervention …

Dissection of regulatory networks that control gene transcription is one of the greatest
challenges of functional genomics. Using human genomic sequences, models for binding …

Although thousands of long noncoding RNAs (lncRNAs) have been annotated, only a
limited number of them have been functionally characterized. Here, we identified an …