Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein
JT Castro, P Azevedo, MJ Fumagalli… - Nature …, 2022 - nature.com
Both T cells and B cells have been shown to be generated after infection with SARS-CoV-2
yet protocols or experimental models to study one or the other are less common. Here, we …
yet protocols or experimental models to study one or the other are less common. Here, we …
Mucosal administration of cycle-di-nucleotide-adjuvanted virosomes efficiently induces protection against influenza H5N1 in mice
T Ebensen, J Debarry, GK Pedersen… - Frontiers in …, 2017 - frontiersin.org
The need for more effective influenza vaccines is highlighted by the emergence of novel
influenza strains, which can lead to new pandemics. There is a growing population of …
influenza strains, which can lead to new pandemics. There is a growing population of …
addavax formulated with PolyI: C as a potential adjuvant of MDCK-based influenza vaccine enhances local, cellular, and antibody protective immune response in mice
X Nian, J Zhang, T Deng, J Liu, Z Gong, C Lv, L Yao… - AAPS …, 2021 - Springer
Poor immune responses to inactivated influenza vaccine can be improved by effective and
safe adjuvants to increase antibody titers and cellular protective response. In our study …
safe adjuvants to increase antibody titers and cellular protective response. In our study …
Tetrameric neuraminidase of influenza A virus is required to induce protective antibody responses in mice
X Deng, Q Wang, M Liu, Q Zheng, F Wu… - Frontiers in …, 2021 - frontiersin.org
Influenza neuraminidase (NA) is able to induce cross-subtype immunity and is considered
as a promising target for the development of universal influenza vaccines. However …
as a promising target for the development of universal influenza vaccines. However …
Supplementation of H7N9 virus-like particle vaccine With recombinant epitope antigen confers full protection against antigenically divergent H7N9 virus in chickens
D Kong, T Chen, X Hu, S Lin, Y Gao, C Ju… - Frontiers in …, 2022 - frontiersin.org
The continuous evolution of the H7N9 avian influenza virus suggests a potential outbreak of
an H7N9 pandemic. Therefore, to prevent a potential epidemic of the H7N9 influenza virus, it …
an H7N9 pandemic. Therefore, to prevent a potential epidemic of the H7N9 influenza virus, it …
[HTML][HTML] Poly (I: C), a double stranded RNA analog, activates the anti-viral DNA sensors in buffalo fibroblasts
Polyinosinic: polycytidylic acid or poly (I: C) is a double stranded RNA analog that is known
for stimulating RNA sensing pathways in a variety of cell culture and animal models …
for stimulating RNA sensing pathways in a variety of cell culture and animal models …
Induction of lung CD8+ T cell responses by consecutive inoculations of a poly (I: C) influenza vaccine
The cytotoxic T lymphocyte (CTL) response plays a key role in host recovery from influenza
virus infection and in subsequent immunity. Compared to natural infection with influenza …
virus infection and in subsequent immunity. Compared to natural infection with influenza …
[HTML][HTML] poly (I: C), chitosan oligosaccharide, and chitosan enhance inactivated GCRV vaccine potency in grass carp Ctenopharyngodon idella
Q Tian, Y Zhang, J Su - Comparative Immunology Reports, 2024 - Elsevier
Vaccination is the most promising strategy to combat infectious diseases. Vaccine adjuvants
are considered as key components in modern vaccinology since they provide the necessary …
are considered as key components in modern vaccinology since they provide the necessary …
Neutralizing antibody-independent immunity to SARS-CoV-2 in hamsters and hACE-2 transgenic mice immunized with a RBD/Nucleocapsid fusion protein
JT Castro, MJ Fumagalli, NS Hojo-Souza, P Azevedo… - BioRxiv, 2021 - biorxiv.org
The nucleocapsid (N) and the receptor binding domain (RBD) of the Spike (S) proteins elicit
robust antibody and T cell responses either in vaccinated or COVID-19 convalescent …
robust antibody and T cell responses either in vaccinated or COVID-19 convalescent …
Analysis of the dose-sparing effect of adjuvanted Sabin-inactivated poliovirus vaccine (sIPV)
Z Li, W Ding, Q Guo, Z Liu, Z Zhu, S Song… - Human Vaccines & …, 2018 - Taylor & Francis
Sabin-based inactivated poliovirus vaccine (sIPV) is gradually replacing live-attenuated oral
polio vaccine (OPV). Sabin-inactivated poliovirus vaccine (sIPV) has played a vital role in …
polio vaccine (OPV). Sabin-inactivated poliovirus vaccine (sIPV) has played a vital role in …