Structural Insights into Selective and Dual Antagonism of EP2 and EP4 Prostaglandin Receptors

Y Wu, H Zhang, J Xu, K Wu, W Hu, C Wu, HE Xu - bioRxiv, 2024 - biorxiv.org
Prostaglandin E2 (PGE2) signaling through EP2 and EP4 receptors plays a crucial role in
inflammation, pain, and cancer progression. Selective and dual antagonists of these …