Background The infectivity of the HIV-1 acute phase has been directly measured only once,
from a retrospectively identified cohort of serodiscordant heterosexual couples in Rakai …

Recently, there has been much debate about the prospects of eliminating HIV from high
endemic countries by a test-and-treat strategy. This strategy entails regular HIV testing in the …

Antiretroviral therapy (ART) reduces the infectiousness of HIV-infected persons, but only
after testing, linkage to care, and successful viral suppression. Thus, a large proportion of …

Objective: HIV-1 epidemics among MSM remain unchecked despite advances in treatment
and prevention paradigms. This study combined viral phylogenetic and behavioural risk …

Though a wide body of observational and model-based evidence underscores the promise
of Universal Test and Treat (UTT) to reduce population-level HIV incidence in high-burden …

The WHO's early-release guideline for antiretroviral treatment (ART) of HIV infection based
on a recent trial conducted in 34 countries recommends starting treatment immediately upon …

Human immunodeficiency virus (HIV) transmission models that include variability in sexual
behavior over time have shown increased incidence, prevalence, and acute-state …

Choosing between strategies to control HIV transmission with antivirals requires
understanding both the dynamics affecting those strategies' effectiveness and what causes …

In the current issue of Clinical Infectious Diseases, de Souza et al [1] present an important
study documenting the challenges in human immunodeficiency virus (HIV) diagnosis using …

Objectives To determine cost-effectiveness of three community-based acute HIV infection
(AHI) testing algorithms compared to HIV antibody testing alone by focusing on the potential …