Head and neck cancer
Head and neck cancer is the seventh most common type of cancer worldwide and comprise
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
of a diverse group of tumours affecting the upper aerodigestive tract. Although many different …
Head and neck squamous cell carcinoma
DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …
[HTML][HTML] Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors
Introduction Head and neck cancer appears to be increasing in incidence, with potential
changes in aetiology proposed. This paper aims to provide a narrative overview of the …
changes in aetiology proposed. This paper aims to provide a narrative overview of the …
NCCN Guidelines® insights: Head and neck cancers, version 1.2022: Featured updates to the NCCN guidelines
JJ Caudell, ML Gillison, E Maghami, S Spencer… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …
Head and neck cancers, version 2.2020, NCCN clinical practice guidelines in oncology
DG Pfister, S Spencer, D Adelstein, D Adkins… - Journal of the National …, 2020 - jnccn.org
Treatment is complex for patients with head and neck (H&N) cancers with specific site of
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …
disease, stage, and pathologic findings guiding treatment decision-making. Treatment …
Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis
Background p16 INK4a (p16) immunohistochemistry is the most widely used biomarker
assay for inferring HPV causation in oropharyngeal cancer in clinical and trial settings …
assay for inferring HPV causation in oropharyngeal cancer in clinical and trial settings …
Oral diseases: a global public health challenge
Oral diseases are among the most prevalent diseases globally and have serious health and
economic burdens, greatly reducing quality of life for those affected. The most prevalent and …
economic burdens, greatly reducing quality of life for those affected. The most prevalent and …
Role of PI3K/AKT pathway in cancer: the framework of malignant behavior
N Jiang, Q Dai, X Su, J Fu, X Feng, J Peng - Molecular biology reports, 2020 - Springer
Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled …
H Mehanna, M Robinson, A Hartley, A Kong, B Foran… - The Lancet, 2019 - thelancet.com
Background The incidence of human papillomavirus (HPV)-positive oropharyngeal cancer,
a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal growth …
a disease affecting younger patients, is rapidly increasing. Cetuximab, an epidermal growth …
The changing therapeutic landscape of head and neck cancer
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …