Herpes simplex virus evasion of early host antiviral responses

EI Tognarelli, TF Palomino, N Corrales… - Frontiers in cellular …, 2019 - frontiersin.org
Herpes simplex viruses type 1 (HSV-1) and type 2 (HSV-2) have co-evolved with humans for
thousands of years and are present at a high prevalence in the population worldwide. HSV …

Disease progression mediated by egr-1 associated signaling in response to oxidative stress

JI Pagel, E Deindl - International journal of molecular sciences, 2012 - mdpi.com
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive
oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and …

Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for …

S Samandary, H Kridane-Miledi, JS Sandoval… - Human immunology, 2014 - Elsevier
A significant portion of the world's population is infected with herpes simplex virus type 1
and/or type 2 (HSV-1 and/or HSV-2), that cause a wide range of diseases including genital …

Evaluation of a nanophosphor lateral-flow assay for self-testing for herpes simplex virus type 2 seropositivity

HJ Goux, B Raja, K Kourentzi, JRC Trabuco, BV Vu… - PloS one, 2019 - journals.plos.org
Herpes Simplex Virus Type 2 (HSV-2) is a common human pathogen that causes life-long
illness. The US prevalence of HSV-2 infection is 11.9% for individuals between 15 and 49 …

The effect of sexually transmitted co-infections on HIV viral load amongst individuals on antiretroviral therapy: a systematic review and meta-analysis

D Champredon, SE Bellan, W Delva, S Hunt… - BMC infectious …, 2015 - Springer
Background Antiretroviral therapy (ART) markedly reduces HIV transmission, and testing
and treatment programs have been advocated as a method for decreasing transmission at …

Seroprevalence of HSV-1 and 2 in HIV-infected males with and without GUD: Study from a tertiary care setting of India

A Munawwar, S Gupta, SK Sharma… - Journal of laboratory …, 2018 - thieme-connect.com
BACKGROUND: Herpes simplex virus (HSV) infection is associated with an increased risk of
both human immune deficiency virus (HIV) transmission and acquisition. However, in India …

Molecular characterization of plasma virome of hepatocellular carcinoma (HCC) patients

N Ullah Khan, A Sadiq, J Khan, N Basharat, ZU Hassan… - AMB Express, 2024 - Springer
Hepatocellular carcinoma (HCC) stands as the most common cancer type, arising from
various causes, and responsible for a substantial number of cancer-related fatalities. Recent …

What is the burden of heterosexually acquired HIV due to HSV-2? Global and regional model-based estimates of the proportion and number of HIV infections …

R Silhol, H Coupland, RF Baggaley… - JAIDS Journal of …, 2021 - journals.lww.com
Background: Biological and epidemiological evidence suggest that herpes simplex virus
type 2 (HSV-2) elevates HIV acquisition and transmission risks. We improved previous …

High rates of herpes simplex virus type 2 infection in homeless women: informing public health strategies

JD Kelly, J Cohen, B Grimes, SS Philip… - Journal of Women's …, 2016 - liebertpub.com
Background: Homeless and unstably housed women living in an urban setting are at risk for
sexually transmitted diseases, yet the seroprevalence and correlates of herpes simplex virus …

Incidence of herpes simplex virus type 2 positivity among women living with human immunodeficiency virus in South Africa

K Asare, S Ngcapu, F Osman… - … journal of STD & …, 2024 - journals.sagepub.com
Background For women living with HIV (WLHIV), co-infection with herpes simplex virus type
2 (HSV-2) causes severe genital ulcers and presents additional challenges for their HIV …